期刊
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
卷 259, 期 5, 页码 1161-1166出版社
SPRINGER
DOI: 10.1007/s00417-020-04961-9
关键词
Adaptive optics; Spectral domain optical coherence tomography; Photoreceptors; Solar retinopathy
Adaptive optics is a sensitive and accurate tool to analyze photoreceptor damage in solar retinopathy patients. It can be used as an adjunct for better understanding of the pathology and to observe or predict changes in these patients.
Background To study the characteristics of photoreceptors on adaptive optics (AO) in patients of solar retinopathy and its correlation to changes in spectral domain optical coherence tomography (SDOCT) and visual acuity. Methods and material This is a cross-sectional observational study of six eyes of five patients with clinically diagnosed solar retinopathy. Five age-matched controls were included for comparison. A flood-illuminated adaptive optics retinal camera (AO; rtx1, Imagine Eyes, Orsay, France) was used to image the photoreceptors and a spectral domain optical coherence tomography (SDOCT; Spectralis (TM) Heidelberg Engineering, Germany) was used to study the retinal layers in these patients. The corrected distance visual acuity (CDVA) was assessed using Snellen's chart. Results Defects on the SDOCT were smaller (0.25 to 0.75 degrees) at the fovea compared with AO (more than 1 degrees). The cone mosaic was preserved beyond 1 degrees. The cone count from the foveal center at 0.75, 1, 2, and 3 degrees was decreased in all patients of solar retinopathy (mean value 5352) compared with age-matched controls (mean value 15693). A corresponding increase in spacing (mean value 19.13) compared with controls (mean value 9.34) was also observed. The CDVA ranged from 20/30 to 20/80. There was no statistically significant relationship between cone density, at any of the eccentricities measured, with CDVA or OCT defect (p> 0.05, for all). Conclusions Adaptive optics is a sensitive and accurate tool to analyze photoreceptor damage in solar maculopathy. It can be used as an adjunct for better understanding of the pathology and to observe or predict changes in these patients.
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