期刊
GENOMICS
卷 113, 期 1, 页码 541-552出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ygeno.2020.09.047
关键词
Artificial neural networks (ANN); Classification; Clinical data; WCC algorithm
This study introduces an efficient approach based on the WCC algorithm and multi-layer perceptron artificial neural network, generating a specific model for each individual data class which yields high accuracy in clinical and biological data classification.
Many data mining methods have been proposed to generate computer-aided diagnostic systems, which may determine diseases in their early stages by categorizing the data into some proper classes. Considering the importance of the existence of a suitable classifier, the present study aims to introduce an efficient approach based on the World Competitive Contests (WCC) algorithm as well as a multi-layer perceptron artificial neural network (ANN). Unlike the previously introduced methods, which each has developed a universal model for all different kinds of data classes, our proposed approach generates a single specific model for each individual class of data. The experimental results show that the proposed method (ANNWCC), which can be applied to both the balanced and unbalanced datasets, yields more than 76% (without applying feature selection methods) and 90% (with applying feature selection methods) of the average five-fold cross-validation accuracy on the 13 clinical and biological datasets. The findings also indicate that under different conditions, our proposed method can produce better results in comparison to some state-of-art meta-heuristic algorithms and methods in terms of various statistical and classification measurements. To classify the clinical and biological data, a multi-layer ANN and the WCC algorithm were combined. It was shown that developing a specific model for each individual class of data may yield better results compared with creating a universal model for all of the existing data classes. Besides, some efficient algorithms proved to be essential to generate acceptable biological results, and the methods' performance was found to be enhanced by fuzzifying or normalizing the biological data.
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