Quantitative evaluation of passive muscle stiffness by shear wave elastography in healthy individuals of different ages

Objectives To investigate age-related changes on passive muscle stiffness in healthy individuals and measure the shear modulus in different age groups. Methods Shear wave elastography (SWE) movies of gastrocnemius medialis (GM) were collected during passive stretching induced by ankle rotation from plantarflexion (PF) to dorsiflexion (DF). A series of SWE images at ankle angles of PF 40 degrees, PF 30 degrees, PF 20 degrees, PF 10 degrees, 0 degrees, DF 10 degrees, DF 20 degrees, and DF 30 degrees were collected and shear moduli measured accordingly for analyses. Results Eighty-six healthy volunteers (27 children, 31 middle-aged adults, and 28 older people) were recruited. No significant difference was observed in the shear modulus between the three groups at ankle angles of PF 40 degrees, PF 30 degrees, PF 20 degrees, PF 10 degrees, and 0 degrees (p> 0.05). The difference in the shear modulus among the three groups became significant as DF increased. At ankle angles of DF 10 degrees, DF 20 degrees, and DF 30 degrees, the shear modulus was the greatest in the older group, followed by the middle-aged group and then the children group (p= 0.007, 0.000, and 0.000, respectively). Conclusions Passive muscle stiffness increases with age, and the difference between age groups was pronounced only after reaching a certain degree of stretching.

Automated summary

The study found that passive muscle stiffness increases with age, and the differences between age groups only become significant after reaching a certain degree of stretching.