期刊
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
卷 2020, 期 37, 页码 5995-5999出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.202001018
关键词
Photocatalysis; Flow chemistry; Aryl-iodine reduction; Cyclization; Photoredox
资金
- European Research Council (ERC-CoG) [647550]
- Spanish Government [RTI2018-095038-B-I00]
- European Structural Funds [S2018/NMT-4367]
- Comunidad de Madrid [IND2019/AMB-17142]
- Comunidad Autonoma de Madrid
In this work, we describe the use of visible light and a photocatalytic system for the cyclization of iodoaryl vinyl derivatives to tetrahydroquinoline structures. The reaction proceeds under very mild conditions, tolerates different functional groups and more importantly, the method allows the synthesis ofN-free tetrahydroquinolines fromN-unprotected starting materials. In addition, the reaction can also be performed using flow-chemistry. Finally, a mechanistic proposal based on some mechanistic studies has been described.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据