期刊
EARLY HUMAN DEVELOPMENT
卷 149, 期 -, 页码 -出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.earlhumdev.2020.105152
关键词
Alzheimer's disease; Dementia; Prenatal androgens; Sex differences; Sexual differentiation
资金
- National Institutes of Health [RF1 AG058068]
- Alzheimer's Association [SAGA-17-419408]
Alzheimer's disease is characterized by sex differences that may involve sex hormone exposure during development. Finger length ratios, an indirect measure of prenatal androgen exposure, were found to significantly differ in women with and without dementia. This finding links a relatively feminine in utero development with vulnerability to dementia in women.
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