期刊
DIABETOLOGIA
卷 63, 期 10, 页码 2086-2094出版社
SPRINGER
DOI: 10.1007/s00125-020-05204-6
关键词
Autonomic nervous system; Brain; Diabetes; Glucagon; Glucose; Insulin; Islet; Pancreas; Review
资金
- American Diabetes Association [ADA 1-19-PDF-103] Funding Source: Medline
- NHLBI NIH HHS [T32 HL007028] Funding Source: Medline
- NIDDK NIH HHS [F31 DK113673, K01 DK126793, R01 DK089056, T32 DK007247, P30 DK017047] Funding Source: Medline
- NIGMS NIH HHS [T32 GM095421] Funding Source: Medline
Increasing evidence suggests that, although pancreatic islets can function autonomously to detect and respond to changes in the circulating glucose level, the brain cooperates with the islet to maintain glycaemic control. Here, we review the role of the central and autonomic nervous systems in the control of the endocrine pancreas, including mechanisms whereby the brain senses circulating blood glucose levels. We also examine whether dysfunction in these systems might contribute to complications of type 1 diabetes and the pathogenesis of type 2 diabetes. Graphical abstract
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据