期刊
DIABETES TECHNOLOGY & THERAPEUTICS
卷 23, 期 3, 页码 230-233出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/dia.2020.0471
关键词
Type 1 diabetes; Time in range; Continuous glucose monitoring; Glycemic control
资金
- Dexcom, Inc.
The DIAMOND study showed that real-time continuous glucose monitors (rtCGMs) can improve glycemia for adults with type 1 diabetes using multiple daily injections. Participants with lower baseline time in range (<40%, <50%, <60%) benefited more from using rtCGMs compared to self-monitoring of blood glucose (SMBG), with significant improvements in mean TIR and reduced time spent in hyper- and hypoglycemic ranges.
The DIAMOND study demonstrated that real-time continuous glucose monitors (rtCGMs) improve glycemia for adults with type 1 diabetes using multiple daily injections. This analysis explores the relationship between baseline time in range (TIR) and improvement in TIR using rtCGMs or self-monitoring of blood glucose (SMBG). Baseline TIR was divided into three categories: <40% (9.6 h per day), <50% (12 h per day), and <60% (14.4 h per day). Compared with SMBG, use of rtCGMs increased mean TIR by an additional 16 min per day for participants with a baseline TIR <40%, 77 min per day for baseline TIR <50%, and 88 min per day for baseline TIR 4 h per day using rtCGMs within the three baseline TIR groups. For participants with a baseline TIR <50%, 29% of rtCGM users improved their TIR by >4 h per day compared with no SMBG users (P < 0.001). Similar trends were found for improvement in mean glucose and time spent in hyper- and hypoglycemic ranges.
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