期刊
DEVELOPMENT GENES AND EVOLUTION
卷 230, 期 5-6, 页码 315-327出版社
SPRINGER
DOI: 10.1007/s00427-020-00667-4
关键词
Mouth formation; Mouth opening; Larvacean; Oikopleura; Coronal sensory cell; Hair cell evolution
资金
- JSPS
- MEXT Japan [26650079, 15H04377, 16K14735, 17KT0023, 19H03234, 24870019, 26840079, 18K06256]
- Inamori Foundation
- Kato Memorial Research Foundation
- Sumitomo Foundation
- Japan Foundation for Applied Enzymology
- JSPS KAKENHI [JP16H06280]
- Advanced Bioimaging Support (ABiS)
Mouth formation involves the processes of mouth opening, formation of the oral cavity, and the development of associated sensory organs. In deuterostomes, the surface ectoderm and the anterior part of the archenteron are reconfigured and reconnected to make a mouth opening. This study of the larval development of the larvacean,Oikopleura dioica, investigates the cellular organization of the oral region, the developmental processes of the mouth, and the formation of associated sensory cells.O. dioicais a simple chordate whose larvae are transparent and have a small number of constituent cells. It completes organ morphogenesis in 7 h, between hatching 3 h after fertilization and the juvenile stage at 10 h, when it attains adult form and starts to feed. It has two types of mechanosensory cell embedded in the oral epithelium, which is a single layer of cells. There are twenty coronal sensory cells in the circumoral nerve ring and two dorsal sensory organ cells. Two bilateral lip precursor cells (LPCs), facing the anterior surface, divide dorsoventrally and make a wedge-shaped cleft between the two daughter cells named the dorsal lip cell (DLC) and the ventral lip cell (VLC). Eventually, the DLC and VLC become detached and separated into dorsal and ventral lips, triggering mouth opening. This is an intriguing example of cell division itself contributing to morphogenesis. The boundary between the ectoderm and endoderm is present between the lip cells and coronal sensory cells. All oral sensory cells, including dorsal sensory organ cells, were of endodermal origin and were not derived from the ectodermal placode. These observations on mouth formation provide a cellular basis for further studies at a molecular level, in this simple chordate.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据