期刊
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
卷 124, 期 -, 页码 121-137出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.cmpb.2015.10.008
关键词
Computerised cardiotocography; Foetal heart rate variability; Nonlinear indices; FHR clinical analysis; Software performance; Matlab
类别
资金
- project Sviluppo di sistemi per il monitoraggio fetale domiciliare - Legge 5 of Campania Region
- DRIVE IN2 project - Italian National Programme Piano Operativo Nazionale Ricerca e Competitivita
Despite the widespread use of cardiotocography in foetal monitoring, the evaluation of foetal status suffers from a considerable inter and intra-observer variability In order to overcome the main limitations of visual cardiotocographic assessment, computerised methods to analyse cardiotocographic recordings have been recently developed. In this study, a new software for automated analysis of foetal heart rate is presented. It allows an automatic procedure for measuring the most relevant parameters derivable from cardiotocographic traces. Simulated and real cardiotocographic traces were analysed to test software reliability. In artificial traces, we simulated a set number of events (accelerations, decelerations and contractions) to be recognised. In the case of real signals, instead, results of the computerised analysis were compared with the visual assessment performed by 18 expert clinicians and three performance indexes were computed to gain information about performances of the proposed software. The software showed preliminary performance we judged satisfactory in that the results matched completely the requirements, as proved by tests on artificial signals in which all simulated events were detected from the software. Performance indexes computed in comparison with obstetricians' evaluations are, on the contrary, not so satisfactory; in fact they led to obtain the following values of the statistical parameters: sensitivity equal to 93%, positive predictive value equal to 82% and accuracy equal to 77%. Very probably this arises from the high variability of trace annotation carried out by clinicians. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
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