期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 64, 期 -, 页码 37-43出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2020.05.020
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资金
- European Research Council ERC Consolidator Grant - TransReg [819717]
- Swiss National Science Foundation grant ForceInRegeneration [310030L_182575]
- Swiss National Science Foundation (SNF) [310030L_182575] Funding Source: Swiss National Science Foundation (SNF)
- European Research Council (ERC) [819717] Funding Source: European Research Council (ERC)
In humans, myocardial infarction results in ventricular remodeling, progressing ultimately to cardiac failure, one of the leading causes of death worldwide. In contrast to the adult mammalian heart, the zebrafish model organism has a remarkable regenerative capacity, offering the possibility to research the bases of natural regeneration. Here, we summarize recent insights into the cellular and molecular mechanisms that govern cardiac regeneration in the zebrafish.
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