期刊
CURRENT OPINION IN CHEMICAL BIOLOGY
卷 58, 期 -, 页码 86-95出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2020.07.004
关键词
Bioremediation; Xenobiotics; Synthetic biology; Heavy metals; Organic pollutants
资金
- Biotechnology and Biological Sciences Research Council (BBSRC)
- UK Ministry of Defence
- Strategic Environmental Research and Development Program (SERDP) of the US Department of Defense
- Environmental Security Technology Certification Program (ESTCP) of the US Department of Defense
The World Health Organization reported that an estimated 12.6 million people died as a result of living or working in an unhealthy environment in 2012, nearly 1 in 4 of total global deaths. Air, water and soil pollution were the significant risk factors, and there is an urgent need for effective remediation strategies. But tackling this problem is not easy; there are many different types of pollutants, often widely dispersed, difficult to locate and identify, and in many cases cost-effective clean-up techniques are lacking. Biology offers enormous potential as a tool to develop microbial and plant-based solutions to remediate and restore our environment. Advances in synthetic biology are unlocking this potential enabling the design of tailor-made organisms for bioremediation. In this article, we showcase examples of xenobiotic clean-up to illustrate current achievements and discuss the limitations to advancing this promising technology to make real-world improvements in the remediation of global pollution.
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