期刊
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
卷 24, 期 5, 页码 467-484出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10255842.2020.1836167
关键词
Arterial wall mechanics; abdominal aortic aneurysm; tunica intima
资金
- Galician Regional Government (Xunta de Galicia) [ED431C 2017/72]
- Spanish Government (Ministerio de Educaci~on Cultura y Deporte)
Experimental data on human aortic tissue show that the innermost layer of the aorta becomes load-bearing in aged arteries and arteries with non-atherosclerotic intimal thickening. However, there is limited computational study on abdominal aortic aneurysms (AAAs) considering the mechanical contribution of the three layers. This paper proposes a three-layered finite element model and analyzes the mechanical contributions of the adventitia, media, and intima in three-layered aneurysms.
Layer-specific experimental data for human aortic tissue suggest that, in aged arteries and arteries with non-atherosclerotic intimal thickening, the innermost layer of the aorta increases significantly its stiffness and thickness, becoming load-bearing. However, there are very few computational studies of abdominal aortic aneurysms (AAAs) that take into account the mechanical contribution of the three layers that comprise the aneurysmal tissue. In this paper, a three-layered finite element model is proposed from the simplest uniaxial stress state to geometrically parametrized models of AAAs with different asymmetry values. Comparisons are made between a three-layered artery wall and a mono-layered intact artery, which represents the complex behavior of the aggregate adventitia-media-intima in a single layer with averaged mechanical properties. Likewise, the response of our idealized geometries is compared with similar experimental and numerical models. Finally, the mechanical contributions of adventitia, media and intima are analyzed for the three-layered aneurysms through the evaluation of the mean stress absorption percentage. Results show the relevance and necessity of considering the inclusion of tunica intima in multi-layered models of AAAs for getting accurate results in terms of peak wall stresses and displacements.
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