Practical and sustainable approach for clean preparation of 5-organylselanyl uracils

An eco-friendly, sustainable and practical method for the efficient preparation of 5-organylselanyl uracils through the electrochemical selenylation of uracils and diorganyl diselenides at room temperature under oxidant- and external electrolyte-free conditions was developed. (C) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

Automated summary

An eco-friendly, sustainable and practical method for efficient preparation of 5-organylselanyl uracils through electrochemical selenylation of uracils has been developed at room temperature under oxidant- and external electrolyte-free conditions.