Hydrogen-Bond-Donor Solvents Enable Catalyst-Free (Radio)-Halogenation and Deuteration of Organoborons

A hydrogen bond donor solvent assisted (radio)halogenation and deuteration of organoborons has been developed. The reactions exhibited high functional group tolerance and needed only an ambient atmosphere. Most importantly, compared to literature methods, our conditions are more consistent with the principals of green chemistry (e.g., metal-free, strong oxidant-free, more straightforward conditions).

Automated summary

A new method for halogenation and deuteration of organoborons using a hydrogen bond donor solvent has been developed, showing high functional group tolerance and environmental friendliness. Compared to literature methods, the conditions are more consistent with the principles of green chemistry.