期刊
CHEMICAL ENGINEERING JOURNAL
卷 408, 期 -, 页码 -出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.cej.2020.127245
关键词
Carbon dots; Nanocarriers; Photothermal therapy; Photodynamic therapy
资金
- National Natural Science Foundation of China [61805287]
- Natural Science Foundation of Hunan Province, China [2019JJ50824]
- Fundamental Research Funds for Central Universities of the Central South University [202045002, 2020zzts404]
- Innovation-Driven Project of Central South University [2020CX021]
- Foundation of Shenzhen Science and Technology Innovation [JCYJ20180307151245919]
Carbon dots, as a novel zero-dimensional carbonaceous nanomaterial, have shown great potential in phototherapy as effective photosensitizers or photothermal agents for cancer treatment, and are expected to play an important role in phototheranostics.
Carbon dots (CDs) are novel zero-dimensional carbonaceous nanomaterial, and they are featured with an attractive combination of physical, chemical, and biomedical properties including wide absorption spectrum, tunable fluorescence, excellent water solubility, outstanding photostability, and biocompatibility, which leads to their diverse applications as optically functional materials in various fields, e.g., fluorescence sensing, bioimaging, and drug delivery. Recently, it was revealed that CDs could be used as an effective photosensitizer to generate reactive oxygen species under light excitation, and/or a photothermal agent to convert light energy into heat, which enable them to be applied in photodynamic therapy or photothermal therapy for cancer treatment. In this review, we summarize the latest progress of research on CDs in phototherapy, including their use as nanocarriers for organic phototherapy agents, and highlight the strategies which are adopted to improve the therapeutic efficacy of CDs-based phototheranostics. Furthermore, we also discuss the challenges and prospects of the CDs-based phototheranostics towards clinical applications. We hope this review will provide critical insights to inspire new exciting discoveries on CDs from both fundamental and practical views so as to prompt their advances in the phototherapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据