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注意：仅列出部分参考文献，下载原文获取全部文献信息。Current and Emerging Treatments of Essential Tremor
William George Ondo
NEUROLOGIC CLINICS (2020)
Inhibition of Excessive Glutamatergic Transmission in the Ventral Thalamic Nuclei by a Selective Adenosine A1 Receptor Agonist, 5′-Chloro-5′-Deoxy-(±)-ENBA Underlies its Tremorolytic Effect in the Harmaline-Induced Model of Essential Tremor
Barbara Kosmowska et al.
NEUROSCIENCE (2020)
Cerebellar oscillations driven by synaptic pruning deficits of cerebellar climbing fibers contribute to tremor pathophysiology
Ming-Kai Pan et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation
Amanda M. Brown et al.
ELIFE (2020)
A Pilot Double-Blind Randomized Trial of Perampanel for Essential Tremor
Adrian Handforth et al.
MOVEMENT DISORDERS CLINICAL PRACTICE (2020)
Non-thermal focused ultrasound induced reversible reduction of essential tremor in a rat model
Shirley Sharabi et al.
BRAIN STIMULATION (2019)
Altered Primary Motor Cortex Neuronal Activity in a Rat Model of Harmaline-Induced Tremor During Thalamic Deep Brain Stimulation
Jihyun Lee et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Perampanel, a new hope for Essential tremor: An open label trial
Alexandre Gironell et al.
PARKINSONISM & RELATED DISORDERS (2019)
Complex spike synchrony dependent modulation of rat deep cerebellar nuclear activity
Tianyu Tang et al.
ELIFE (2019)
Consensus Statement on the Classification of Tremors. From the Task Force on Tremor of the International Parkinson and Movement Disorder Society
Kailash P. Bhatia et al.
MOVEMENT DISORDERS (2018)
Increased glutamate plus glutamine levels in the thalamus of patients with essential tremor: A preliminary proton MR spectroscopic study
Gaetano Barbagallo et al.
PARKINSONISM & RELATED DISORDERS (2018)
Climbing fiber-Purkinje cell synaptic pathology across essential tremor subtypes
Danielle Lee et al.
PARKINSONISM & RELATED DISORDERS (2018)
In Vivo Dentate Nucleus Gamma-aminobutyric Acid Concentration in Essential Tremor vs. Controls
Elan D. Louis et al.
CEREBELLUM (2018)
The Roles of the Olivocerebellar Pathway in Motor Learning and Motor Control. A Consensus Paper
Eric J. Lang et al.
CEREBELLUM (2017)
The differentiated networks related to essential tremor onset and its amplitude modulation after alcohol intake
David J. Pedrosa et al.
EXPERIMENTAL NEUROLOGY (2017)
Tremorolytic effect of 5-chloro-5-deoxy-(±)-ENBA, a potent and selective adenosine A1 receptor agonist, evaluated in the harmaline-induced model in rats
Barbara Kosmowska et al.
CNS NEUROSCIENCE & THERAPEUTICS (2017)
Linking Essential Tremor to the Cerebellum: Physiological Evidence
Pavel Filip et al.
CEREBELLUM (2016)
Synchrony is Key: Complex Spike Inhibition of the Deep Cerebellar Nuclei
Tianyu Tang et al.
CEREBELLUM (2016)
Linking Essential Tremor to the Cerebellum-Animal Model Evidence
Adrian Handforth
CEREBELLUM (2016)
Determinants of rebound burst responses in rat cerebellar nuclear neurons to physiological stimuli
Steven Dykstra et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
Hypertrophic Olivary Degeneration Does Not Reduce Essential Tremor
Ahmad Elkouzi et al.
MOVEMENT DISORDERS CLINICAL PRACTICE (2016)
Integration of Purkinje Cell Inhibition by Cerebellar Nucleo-Olivary Neurons
Marion Najac et al.
JOURNAL OF NEUROSCIENCE (2015)
Abnormal climbing fibre-Purkinje cell synaptic connections in the essential tremor cerebellum
Chi-Ying Lin et al.
BRAIN (2014)
Matching Asymmetry of Tremor with Asymmetry of Postmortem Cerebellar Hemispheric Changes in Essential Tremor
Elan D. Louis et al.
CEREBELLUM (2014)
Behavioral Correlates of Complex Spike Synchrony in Cerebellar Microzones
Jornt R. De Gruijl et al.
JOURNAL OF NEUROSCIENCE (2014)
Reduced cortical plasticity and GABAergic modulation in essential tremor
Wen-Li Chuang et al.
MOVEMENT DISORDERS (2014)
NMDA Receptor Activation Strengthens Weak Electrical Coupling in Mammalian Brain
Josef Turecek et al.
NEURON (2014)
Purkinje cell axonal anatomy: quantifying morphometric changes in essential tremor versus control brains
Rachel Babij et al.
BRAIN (2013)
Cerebellar rTMS stimulation may induce prolonged clinical benefits in essential tremor, and subjacent changes in functional connectivity: An open label trial
T. Popa et al.
BRAIN STIMULATION (2013)
Compensatory Molecular and Functional Mechanisms in Nervous System of the Grm1crv4 Mouse Lacking the mGlu1 Receptor: A Model for Motor Coordination Deficits
Pia Irene Anna Rossi et al.
CEREBRAL CORTEX (2013)
Quantification of Cerebellar Hemispheric Purkinje Cell Linear Density: 32 ET Cases Versus 16 Controls
Elan D. Louis et al.
MOVEMENT DISORDERS (2013)
PATTERNS OF mRNA AND PROTEIN EXPRESSION FOR 12 GABAA RECEPTOR SUBUNITS IN THE MOUSE BRAIN
H. Hoertnagl et al.
NEUROSCIENCE (2013)
Disruption of cerebellar microzonal organization in GluD2 (GluR delta 2) knockout mouse
Miki Hashizume et al.
FRONTIERS IN NEURAL CIRCUITS (2013)
Positive Allosteric Modulation of AMPA Receptors from Efficacy to Toxicity: The Interspecies Exposure-Response Continuum of the Novel Potentiator PF-4778574
Christopher L. Shaffer et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
Subcortical Neuronal Ensembles: An Analysis of Motor Task Association, Tremor, Oscillations, and Synchrony in Human Patients
Timothy L. Hanson et al.
JOURNAL OF NEUROSCIENCE (2012)
Purkinje neuron synchrony elicits time-locked spiking in the cerebellar nuclei
Abigail L. Person et al.
NATURE (2012)
Molecular mechanism of parallel fiber-Purkinje cell synapse formation
Masayoshi Mishina et al.
FRONTIERS IN NEURAL CIRCUITS (2012)
Compartmentalization of the Deep Cerebellar Nuclei Based on Afferent Projections and Aldolase C Expression
Izumi Sugihara
CEREBELLUM (2011)
Control of Cerebellar Nuclear Cells: A Direct Role for Complex Spikes?
Eric J. Lang et al.
CEREBELLUM (2011)
Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABAA receptors
Pratap Meera et al.
JOURNAL OF NEUROPHYSIOLOGY (2011)
An Open-Label, Single-Dose, Crossover Study of the Pharmacokinetics and Metabolism of Two Oral Formulations of 1-Octanol in Patients with Essential Tremor
Fatta B. Nahab et al.
NEUROTHERAPEUTICS (2011)
In Vivo Analysis of Inhibitory Synaptic Inputs and Rebounds in Deep Cerebellar Nuclear Neurons
Fredrik Bengtsson et al.
PLOS ONE (2011)
Ablation of Glutamate Receptor GluRδ2 in Adult Purkinje Cells Causes Multiple Innervation of Climbing Fibers by Inducing Aberrant Invasion to Parallel Fiber Innervation Territory
Taisuke Miyazaki et al.
JOURNAL OF NEUROSCIENCE (2010)
Disappearance of Essential Tremor After Stroke
Michel J.-M. Dupuis et al.
MOVEMENT DISORDERS (2010)
T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor
Adrian Handforth et al.
NEUROPHARMACOLOGY (2010)
Differential olivo-cerebellar cortical control of rebound activity in the cerebellar nuclei
Freek E. Hoebeek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
CaV3.1 is a tremor rhythm pacemaker in the inferior olive
Young-Gyun Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Pharmacological characterization of harmaline-induced tremor activity in mice
Neil E. Paterson et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Role of the metabotropic glutamate receptor subtype 1 in the Harmaline-induced tremor in rats
Waclaw Kolasiewicz et al.
JOURNAL OF NEURAL TRANSMISSION (2009)
Local Changes in the Excitability of the Cerebellar Cortex Produce Spatially Restricted Changes in Complex Spike Synchrony
Sarah P. Marshall et al.
JOURNAL OF NEUROSCIENCE (2009)
Synchronized Brain Network Associated with Essential Tremor as Revealed by Magnetoencephalography
Alfons Schnitzler et al.
MOVEMENT DISORDERS (2009)
Encoding of Oscillations by Axonal Bursts in Inferior Olive Neurons
Alexandre Mathy et al.
NEURON (2009)
Automated Analysis of Cellular Signals from Large-Scale Calcium Imaging Data
Eran A. Mukamel et al.
NEURON (2009)
Thalamic deep brain stimulation improves eyeblink conditioning deficits in essential tremor
M. Kronenbuerger et al.
EXPERIMENTAL NEUROLOGY (2008)
Purkinje-cell-restricted restoration of Kv3.3 function restores complex spikes and rescues motor coordination in Kcnc3 mutants
Edward C. Hurlock et al.
JOURNAL OF NEUROSCIENCE (2008)
Kv3.3 channels at the Purkinje cell soma are necessary for generation of the classical complex spike waveform
Edward Zagha et al.
JOURNAL OF NEUROSCIENCE (2008)
Questioning the role of rebound firing in the cerebellum
Karina Alvina et al.
NATURE NEUROSCIENCE (2008)
Molecular mechanisms governing competitive synaptic wiring in cerebellar Purkinje cells
Masahiko Watanabe
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor
Lane Bekar et al.
NATURE MEDICINE (2008)
Altered olivocerebellar activity patterns in the connexin36 knockout mouse
Sarah P. Marshall et al.
CEREBELLUM (2007)
Spontaneous and induced mouse mutations with cerebellar dysfunctions: Behavior and neurochemistry
R. Lalonde et al.
BRAIN RESEARCH (2007)
Relationship of complex spike synchrony bands and climbing fiber projection determined by reference to aldolase C compartments in Crus IIa of the rat cerebellar cortex
Izumi Sugihara et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2007)
Number and density of AMPA receptors in individual synapses in the rat cerebellum as revealed by SDS-digested freeze-fracture replica labeling
Miwako Masugi-Tokita et al.
JOURNAL OF NEUROSCIENCE (2007)
Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei
Marylka Uusisaari et al.
JOURNAL OF NEUROPHYSIOLOGY (2007)
Altered olivocerebellar activity patterns in the connexin36 knockout mouse
Sarah P. Marshall et al.
CEREBELLUM (2007)
Olivocerebellar modulation of motor cortex ability to generate vibrissal movements in rat
EJ Lang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Block of inferior olive gap junctional coupling decreases Purkinje cell complex spike synchrony and Rhythmicity
TA Blenkinsop et al.
JOURNAL OF NEUROSCIENCE (2006)
Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor
Fredricka C. Martin et al.
MOVEMENT DISORDERS (2006)
Physiological and pathological oscillatory networks in the human motor system
A Schnitzler et al.
JOURNAL OF PHYSIOLOGY-PARIS (2006)
Role of gap junctions in synchronized neuronal oscillations in the inferior olive
E Leznik et al.
JOURNAL OF NEUROPHYSIOLOGY (2005)
Exacerbation of harmaline-induced tremor by imipramine
M Arshaduddin et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2005)
Harmaline-induced tremor as a potential preclinical screening method for essential tremor medications
FC Martin et al.
MOVEMENT DISORDERS (2005)
Citalopram, a selective serotonin reuptake inhibitor augments harmaline-induced tremor in rats
M Arshaduddin et al.
BEHAVIOURAL BRAIN RESEARCH (2004)
Allele-dependent changes of olivocerebellar circuit properties in the absence of the voltage-gated potassium channels Kv3.1 and Kv3.3
A McMahon et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Harmaline-induced climbing fiber activation causes amino acid and peptide release in the rodent cerebellar cortex and a unique temporal pattern of Fos expression in the olivo-cerebellar pathway
AJ Beitz et al.
JOURNAL OF NEUROCYTOLOGY (2004)
Ethanol enhances α4β3δ and α6β3δ γ-aminobutyric acid type A receptors at low concentrations known to affect humans
M Wallner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice
H Mehta et al.
BEHAVIOURAL BRAIN RESEARCH (2003)
Abnormal spontaneous and harmaline-stimulated Purkinje cell activity in the awake genetically dystonic rat
MS LeDoux et al.
EXPERIMENTAL BRAIN RESEARCH (2002)
9-carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824):: Selective anticonvulsive and neuroprotective AMPA antagonist
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BIOORGANIC & MEDICINAL CHEMISTRY (2002)
Electrotonically mediated oscillatory patterns in neuronal ensembles:: An in vitro voltage-dependent dye-imaging study in the inferior olive
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JOURNAL OF NEUROSCIENCE (2002)
GABAergic and glutamatergic modulation of spontaneous and motor-cortex-evoked complex spike activity
EJ Lang
JOURNAL OF NEUROPHYSIOLOGY (2002)
Stimulus-dependent activation of c-Fos in neurons and glia in the rat cerebellum
JB Tian et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2002)
Organization of olivocerebellar activity in the absence of excitatory glutamatergic input
EJ Lang
JOURNAL OF NEUROSCIENCE (2001)
Differential expression of c-Fos following administration of two tremorgenic agents: harmaline and oxotremorine
H Miwa et al.
NEUROREPORT (2000)
Expression of connexin36 in the adult and developing rat brain
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BRAIN RESEARCH (2000)
Paraneoplastic cerebellar ataxia due to autoantibodies against a glutamate receptor
PS Smitt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
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