相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Intrinsic Differential Scanning Fluorimetry for Fast and Easy Identification of Adeno-Associated Virus Serotypes
Ruth Rieser et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening
Kathleen Boerner et al.
MOLECULAR THERAPY (2020)
AAV Vector Immunogenicity in Humans: A Long Journey to Successful Gene Transfer
Helena Costa Verdera et al.
MOLECULAR THERAPY (2020)
Engineering adeno-associated virus vectors for gene therapy
Chengwen Li et al.
NATURE REVIEWS GENETICS (2020)
In vitro assay for the efficacy assessment of AAV vectors expressing microdystrophin
Kirill A. Danilov et al.
EXPERIMENTAL CELL RESEARCH (2020)
Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries
Pauline F. Schmit et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2020)
TPP Combined with DGUC as an Economic and Universal Process for Large-Scale Purification of AAV Vectors
Zhe Yu et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2020)
Adeno-associated virus vector as a platform for gene therapy delivery
Dan Wang et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
Cav3.2T-type calcium channels shape electrical firing in mouse Lamina II neurons
Miriam Candelas et al.
SCIENTIFIC REPORTS (2019)
Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome
Fanny Collaud et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors
Hildegard Buning et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Gene manipulation in liver ductal organoids by optimized recombinant adeno-associated virus vectors
Jinsong Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells
Daniel Blessing et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Post-translational modifications in capsid proteins of recombinant adeno-associated virus (AAV) 1-rh10 serotypes
Bertin Mary et al.
FEBS JOURNAL (2019)
Removal of Endotoxin from rAAV Samples Using a Simple Detergent-Based Protocol
Liudmyla Kondratova et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Developing an Anion Exchange Chromatography Assay for Determining Empty and Full Capsid Contents in AAV6.2
Chunlei Wang et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design
Pierce J. Ogden et al.
SCIENCE (2019)
Production of adeno-associated virus vectors for in vitro and in vivo applications
Toyokazu Kimura et al.
SCIENTIFIC REPORTS (2019)
Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings
Lucy H. Maynard et al.
HUMAN GENE THERAPY METHODS (2019)
Evaluation of AAV-DJ vector for retinal gene therapy
Yusaku Katada et al.
PEERJ (2019)
Targeting Adeno-Associated Virus Vectors for Local Delivery to Fractures and Systemic Delivery to the Skeleton
Lucinda R. Lee et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Sex differences in olfactory-induced neural activation of the amygdala
Takefumi Kikusui et al.
BEHAVIOURAL BRAIN RESEARCH (2018)
A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency
Julie Tordo et al.
BRAIN (2018)
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity
Nicole K. Paulk et al.
MOLECULAR THERAPY (2018)
Adeno-Associated Viral Vector Serotype DJ-Mediated Overexpression of N171-82Q-Mutant Huntingtin in the Striatum of Juvenile Mice Is a New Model for Huntington's Disease
Minhee Jang et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
AAVvector-mediated in vivo reprogramming into pluripotency
Elena Senis et al.
NATURE COMMUNICATIONS (2018)
Pharmacology of Recombinant Adeno-associated Virus Production
Magalie Penaud-Budloo et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2018)
Universal Method for the Purification of Recombinant AAV Vectors of Differing Serotypes
Shelley A. Nass et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2018)
Helper-free Production of Laboratory Grade AAV and Purification by lodixanol Density Gradient Centrifugation
Sean M. Crosson et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2018)
Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function
April R. Giles et al.
MOLECULAR THERAPY (2018)
Site-Specific N-Glycosylation on the AAV8 Capsid Protein
Arya Aloor et al.
VIRUSES-BASEL (2018)
Chimeric Adeno-Associated Virus-Mediated Cardiovascular Reprogramming for Ischemic Heart Disease
So Young Yoo et al.
ACS OMEGA (2018)
Molecular design for recombinant adeno-associated virus (rAAV) vector production
Juan Jose Aponte-Ubillus et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2018)
Empty Adeno-Associated Virus Capsids: Contaminant or Natural Decoy?
Terence R. Flotte
HUMAN GENE THERAPY (2017)
Unraveling the Complex Story of Immune Responses to AAV Vectors Trial After Trial
Celine Vandamme et al.
HUMAN GENE THERAPY (2017)
Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells
Oleksandr Kondratov et al.
MOLECULAR THERAPY (2017)
AAV-ID: A Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations
Simon Pacouret et al.
MOLECULAR THERAPY (2017)
Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity
Jun Xie et al.
MOLECULAR THERAPY (2017)
In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models
Chaoran Yin et al.
MOLECULAR THERAPY (2017)
Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c
Bifeng Pan et al.
NATURE BIOTECHNOLOGY (2017)
A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear
Lukas D. Landegger et al.
NATURE BIOTECHNOLOGY (2017)
Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion
Longping Victor Tse et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Next-generation AAV vectors for clinical use: an ever-accelerating race
Jonas Weinmann et al.
VIRUS GENES (2017)
Efficient production of recombinant adeno-associated viral vector, serotype DJ/8, carrying the GFP gene
Haruo Hashimoto et al.
VIRUS RESEARCH (2017)
Assaying the Stability and Inactivation of AAV Serotype 1 Vectors
Douglas B. Howard et al.
HUMAN GENE THERAPY METHODS (2017)
Accurate Identification and Quantification of DNA Species by Next-Generation Sequencing in Adeno-Associated Viral Vectors Produced in Insect Cells
Magalie Penaud-Budloo et al.
HUMAN GENE THERAPY METHODS (2017)
Direct Liquid Chromatography/Mass Spectrometry Analysis for Complete Characterization of Recombinant Adeno-Associated Virus Capsid Proteins
Xiaoying Jin et al.
HUMAN GENE THERAPY METHODS (2017)
The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide
Qing Xie et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2017)
Thermal Stability as a Determinant of AAV Serotype Identity
Antonette Bennett et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2017)
Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction
Jun Suzuki et al.
SCIENTIFIC REPORTS (2017)
Update on the renal toxicity of iodinated contrast drugs used in clinical medicine
Michele Andreucci et al.
DRUG HEALTHCARE AND PATIENT SAFETY (2017)
Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells
Verena V. Emmerling et al.
BIOTECHNOLOGY JOURNAL (2016)
Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells
Verena V. Emmerling et al.
BIOTECHNOLOGY JOURNAL (2016)
Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry
Elizabeth E. Pierson et al.
ANALYTICAL CHEMISTRY (2016)
Single point mutation in adeno-associated viral vectors - DJ capsid leads to improvement for gene delivery in vivo
Yingying Mao et al.
BMC BIOTECHNOLOGY (2016)
Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector
Joshua C. Grieger et al.
MOLECULAR THERAPY (2016)
Simple Purification of Adeno-Associated Virus-DJ for Liver-Specific Gene Expression
Jingjing Liu et al.
YONSEI MEDICAL JOURNAL (2016)
Manufacturing of recombinant adeno-associated viral vectors for clinical trials
Nathalie Clement et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2016)
Scalable Downstream Strategies for Purification of Recombinant Adeno-Associated Virus Vectors in Light of the Properties
Weihong Qu et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2015)
Local administration of AAV-DJ pseudoserotype expressing COX2 provided early onset of transgene expression and promoted bone fracture healing in mice
R. Lakhan et al.
GENE THERAPY (2015)
E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal-Tailored Acceleration of AAV Evolution
Dirk Grimm et al.
MOLECULAR THERAPY (2015)
In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector
Eric Zinn et al.
CELL REPORTS (2015)
Comparative Analysis of Cesium Chloride- and Iodixanol-Based Purification of Recombinant Adeno-Associated Viral Vectors for Preclinical Applications
Benjamin Strobel et al.
HUMAN GENE THERAPY METHODS (2015)
Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin
Qiang Wang et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2015)
OneBac: Platform for Scalable and High-Titer Production of Adeno-Associated Virus Serotype 1-12 Vectors for Gene Therapy
Mario Mietzsch et al.
HUMAN GENE THERAPY (2014)
Defining the Stoichiometry and Cargo Load of Viral and Bacterial Nanoparticles by Orbitrap Mass Spectrometry
Joost Snijder et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Somatic Correction of Junctional Epidermolysis Bullosa by a Highly Recombinogenic AAV Variant
Sandra P. Melo et al.
MOLECULAR THERAPY (2014)
Engineering adeno-associated viruses for clinical gene therapy
Melissa A. Kotterman et al.
NATURE REVIEWS GENETICS (2014)
Proteomics Analysis of Co-Purifying Cellular Proteins Associated with rAAV Vectors
Biao Dong et al.
PLOS ONE (2014)
Empty virions in AAV8 vector preparations reduce transduction efficiency and may cause total viral particle dose-limiting side effects
Kai Gao et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2014)
Comparative Analysis of Adeno-Associated Virus Capsid Stability and Dynamics
Vamseedhar Rayaprolu et al.
JOURNAL OF VIROLOGY (2013)
Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys
Federico Mingozzi et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
A simplified purification method for AAV variant by polyethylene glycol aqueous two-phase partitioning
Ping Guo et al.
BIOENGINEERED (2013)
Evidence for pH-Dependent Protease Activity in the Adeno-Associated Virus Capsid
Maxim Salganik et al.
JOURNAL OF VIROLOGY (2012)
Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector
Dawn E. Bowles et al.
MOLECULAR THERAPY (2012)
Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5 Å Resolution
Thomas F. Lerch et al.
STRUCTURE (2012)
Analysis of Particle Content of Recombinant Adeno-Associated Virus Serotype 8 Vectors by Ion-Exchange Chromatography
Martin Lock et al.
HUMAN GENE THERAPY METHODS (2012)
Efficient Production of Fah-Null Heterozygote Pigs by Chimeric Adeno-Associated Virus-Mediated Gene Knockout and Somatic Cell Nuclear Transfer
Raymond D. Hickey et al.
HEPATOLOGY (2011)
Production, Purification and Characterization of Adeno-Associated Vectors
Eduard Ayuso et al.
CURRENT GENE THERAPY (2010)
Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle
Aravind Asokan et al.
NATURE BIOTECHNOLOGY (2010)
Adenovirus-Adeno-Associated Virus Hybrid for Large-Scale Recombinant Adeno-Associated Virus Production
Hongwei Zhang et al.
HUMAN GENE THERAPY (2009)
Scalable Purification of Adeno-Associated Virus Serotype 1 (AAV1) and AAV8 Vectors, Using Dual Ion-Exchange Adsorptive Membranes
Takashi Okada et al.
HUMAN GENE THERAPY (2009)
Transient Transfection Methods for Clinical Adeno-Associated Viral Vector Production
J. Fraser Wright
HUMAN GENE THERAPY (2009)
Scalable Recombinant Adeno-Associated Virus Production Using Recombinant Herpes Simplex Virus Type 1 Coinfection of Suspension-Adapted Mammalian Cells
Darby L. Thomas et al.
HUMAN GENE THERAPY (2009)
Adeno-associated virus capsid serotype identification: Analytical methods development and application
Kim Van Vliet et al.
JOURNAL OF VIROLOGICAL METHODS (2009)
A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells
Richard H. Smith et al.
MOLECULAR THERAPY (2009)
A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection
Lin Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Critical assessment of current adeno-associated viral vector production and quantification methods
Marc G. Aucoin et al.
BIOTECHNOLOGY ADVANCES (2008)
In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses
Dirk Grimm et al.
JOURNAL OF VIROLOGY (2008)
Engineering and selection of shuffled AAV genomes: A new strategy for producing targeted biological nanoparticles
Wuping Li et al.
MOLECULAR THERAPY (2008)
DNA shuffling of adeno-associated virus yields functionally diverse viral progeny
James T. Koerber et al.
MOLECULAR THERAPY (2008)
High-titer, serum-free production of adeno-associated virus vectors by polyethyleneimine-mediated plasmid transfection in mammalian suspension cells
Markus Hildinger et al.
BIOTECHNOLOGY LETTERS (2007)
Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells
Yves Durocher et al.
JOURNAL OF VIROLOGICAL METHODS (2007)
Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography
Guang Qu et al.
JOURNAL OF VIROLOGICAL METHODS (2007)
Development of AAV serotype-specific ELISAs using novel monoclonal antibodies
Dirk Kuck et al.
JOURNAL OF VIROLOGICAL METHODS (2007)
Scalable production of adeno-associated virus type 2 vectors via suspension transfection
Joon Young Park et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Characterization of the capsid protein glycosylation of adeno-associated virus type 2 by high-resolution mass spectrometry
Sarah Murray et al.
JOURNAL OF VIROLOGY (2006)
Removal of empty capsids from type 1 adeno-associated virus vector stocks by anion-exchange chromatography potentiates transgene expression
M Urabe et al.
MOLECULAR THERAPY (2006)
Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells
M Urabe et al.
JOURNAL OF VIROLOGY (2006)
Production and characterization of adeno-associated viral vectors
Joshua C. Grieger et al.
NATURE PROTOCOLS (2006)
Evidence for encapsidation of prokaryotic sequences during recombinant adeno-associated virus production and their in vivo persistence after vector delivery
G Chadeuf et al.
MOLECULAR THERAPY (2005)
Adeno-associated viral vectors for clinical gene transfer studies
RO Snyder et al.
CURRENT GENE THERAPY (2005)
Impurity of recombinant adeno-associated virus type 2 affects the transduction characteristics following subretinal injection in the rat
WY Shen et al.
VISION RESEARCH (2004)
Purification of recombinant adeno-associated virus type 8 vectors by ion exchange chromatography generates clinical grade vector stock
AM Davidoff et al.
JOURNAL OF VIROLOGICAL METHODS (2004)
Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6
D Grimm et al.
MOLECULAR THERAPY (2003)
A versatile and scalable two-step ion-exchange chromatography process for the purification of recombinant adeno-associated virus serotypes-2 and-5
N Brument et al.
MOLECULAR THERAPY (2002)
Insect cells as a factory to produce adeno-associated virus type 2 vectors
M Urabe et al.
HUMAN GENE THERAPY (2002)
Scalable purification of adeno-associated virus type 2, 4, or 5 using ion-exchange chromatography
N Kaludov et al.
HUMAN GENE THERAPY (2002)
Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo
GP Gao et al.
HUMAN GENE THERAPY (2000)
Cation-exchange high-performance liquid chromatography of recombinant adeno-associated virus type 2
D Debelak et al.
JOURNAL OF CHROMATOGRAPHY B (2000)
分享论文
