期刊
BIOSENSORS & BIOELECTRONICS
卷 166, 期 -, 页码 -出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2020.112447
关键词
Biochemical sensor; Microfluidic chip; Fiber-optic sensor; Application
类别
资金
- National Natural Science Foundation of China [61933004, 61773102]
- Fundamental Research Funds for the Central Universities [N180406003]
- State Key Laboratory of Synthetical Automation for Process Industries [2013ZCX09]
An overview of applications of fiber-optic biochemical sensor in microfluidic chips was carried out with a specific focus on different fiber-optic sensors used on chip, detection methods and biochemical application. First, the structure and sensing mechanism of different fiber-optic sensors used on chip was introduced. Second, optical detection methods in microfluidic chips combined with optical fibers and the advantages and disadvantages of each method were introduced and analyzed in detail. Then, applications of fiber-optic biochemical sensors in microfluidic sensor chips in detecting nucleic acids, proteins, cells, chemicals and microfluidic flow rate were classified and introduced, and different fiber-optic biochemical sensors in microfluidic chip were compared. Finally, a prospect of future development of fiber-optic biochemical sensor combined with microfluidic chip was addressed.
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