4.5 Article

Probiotics: a Promising Generation of Heavy Metal Detoxification

期刊

BIOLOGICAL TRACE ELEMENT RESEARCH
卷 199, 期 6, 页码 2406-2413

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SPRINGERNATURE
DOI: 10.1007/s12011-020-02350-1

关键词

Probiotics; Heavy metals; Lactobacillus; Bifidobacterium

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Various environmental toxins, especially heavy metals, have toxic effects on biological systems. Probiotics, such as Lactobacillus and Bifidobacterium, play a beneficial role in eliminating heavy metals like aluminum, cadmium, lead, or arsenic, reducing their toxic impacts. Probiotics are important for maintaining human health and their detoxification abilities have been studied extensively.
Different environmental toxins especially heavy metals exist in soil, water, and air recording toxic effect on human, animal, and plant. These toxicant elements are widespread in environment causing various disturbances in biological systems. Numerous strategies have been applied recently to alleviate heavy metal contamination; however, most of these strategies were costly and seemed unfriendly to our environment. Probiotics are living cell bacteria with beneficial characteristics for human health.LactobacillusandBifidobacteriumare the major probiotic groups; however,Pediococcus,Lactococcus,Bacillus, andyeastsare recorded as probiotic. The vital role of the probiotics on maintenance of body health was previously investigated. Probiotics were previously recorded to its powerful capacity to bind numerous targets and eliminate them with feces. These targets may be aluminum, cadmium, lead, or arsenic. The current review discusses the history of probiotics, detoxification role of probiotics caused by heavy metals, and mechanism of their action that modulate different signaling pathway disturbance associated with heavy metal accumulation in biological system.

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