期刊
ANTICANCER RESEARCH
卷 40, 期 10, 页码 5351-5354出版社
INT INST ANTICANCER RESEARCH
DOI: 10.21873/anticanres.14542
关键词
Breast cancer; neo-adjuvant chemotherapy; sentinel node biopsy; axillary disease; review
类别
资金
- Breast Cancer Hope Foundation, U.K.
Background/Aim: The treatment of breast cancer has progressed considerably over the years, with a significant de-escalation from radical mastectomies to the current paradigm of breast conserving surgery (BCS) and neoadjuvant chemotherapy (NACT). We aimed to appraise the literature regarding the feasibility of de-escalation of treatment of axillary disease in the context of NACT. Materials and Methods: We appraised studies and guidelines published regarding this topic and discussed them in this mini-review. Results and Conclusion: The SNB following NACT is oncologically safe in patients with clinically node negative disease and in patients with biopsy proven axillary node involvement at presentation provided that the dual technique is used and the clipped pathological node is harvested.
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