期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 60, 期 1, 页码 237-241出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.202008104
关键词
cascade reactions; catalysis; compartmentalization; emulsion polymerization; microreactors
资金
- China Scholarship Council
- German Research Foundation (DFG) through the Emmy Noether Programm [GR 5075/2-1]
- Projekt DEAL
Core-shell microparticles (CSMs) were successfully synthesized with an acid catalyst in the core and a base catalyst in the shell by surfactant-free emulsion polymerization (SFEP). These CSMs exhibited excellent catalytic performance in a model cascade reaction, making them promising candidates for organocatalytic applications in various solvents.
We report on the synthesis of core-shell microparticles (CSMs) with an acid catalyst in the core and a base catalyst in the shell by surfactant-free emulsion polymerization (SFEP). The organocatalytic monomers were separately copolymerized in three synthetic steps allowing the spatial separation of incompatible acid and base catalysts within the CSMs. Importantly, a protected and thermo-decomposable sulfonate monomer was used as acid source to circumvent the neutralization of the base catalyst during shell formation, which was key to obtain stable, catalytically active CSMs. The catalysts showed excellent performance in an established one-pot model cascade reaction in various solvents (including water), which involved an acid-catalyzed deacetalization followed by a base-catalyzed Knoevenagel condensation. The CSMs are easily recycled, modified, and their synthesis is scalable, making them promising candidates for organocatalytic applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据