4.6 Article

Male-to-Female Presumed Transmission of Toxoplasmosis Between Sexual Partners

期刊

AMERICAN JOURNAL OF EPIDEMIOLOGY
卷 190, 期 3, 页码 386-392

出版社

OXFORD UNIV PRESS INC
DOI: 10.1093/aje/kwaa198

关键词

risk factors; semen; sexually transmitted diseases; Toxoplasma

资金

  1. Charles University Grant Agency [104218]
  2. Czech Science Foundation [18-13692S]
  3. Charles University Research Center Program [204056]
  4. Ministry of Health of the Czech Republic [RVO-VFN64165]

向作者/读者索取更多资源

The study found that the seropositivity of male partners for toxoplasmosis may increase the risk of infection in females, supporting the hypothesis of sexual transmission of T. gondii. Although the risk of transmission seems relatively low, it can occur during unprotected sexual intercourse, potentially at the time of conception.
Toxoplasmosis is one of the most widespread human parasitoses in developed countries. Sexual transmission has been confirmed in several animal species, and indirect evidence suggests it may occur in humans. We compared the seropositivity to Toxoplasma gondii in couples who visited the Center for Assisted Reproduction in Prague from June 2016 to June 2018 and analyzed various risk factors including the serological status of sexual partner. By comparing the risk factors in men and women, we tested the hypothesis of male-to-female sexual transmission of toxoplasmosis. The prevalence of toxoplasmosis in women with infected male partners (25.6%; n = 156) was higher than in women with uninfected male partners (18.2%; n = 477; P = 0.045). Therefore, a partner's seropositivity seems to be a risk factor for infection in women (n = 593; prevalence ratio = 1.418; P = 0.045) but not in men (n = 573; prevalence ratio = 1.058; P = 0.816). Our results support the hypothesis of the sexual transmission of T. gondii from men to women. The risk may seem relatively low, but transmission can occur during unprotected sexual intercourse, which may be at the time of conception. Because of the risk of congenital toxoplasmosis, a lower risk of infection than that observed in our study can represent a serious health problem.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据