期刊
SURFACES AND INTERFACES
卷 19, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.surfin.2020.100501
关键词
Magnesium alloy; Corrosion resistance; Polydopamine; Hydroxyapatite coating; Biocompatibility
类别
资金
- National Natural Science Foundation of China [51362006]
- Guangxi Natural Science Foundation [2016GXNSFDA380026, 2017GXNSFAA198112]
- Science and Technology Major Project of Guangxi (Research and industrial application of oxygen enriched melting pool smelting technology for jamesonite) [GXNS2019-182]
Although magnesium alloys have become a promising candidate for bone implant materials, their rapid degradation has limited their use in medical applications. Surface modification is a feasible strategy for solving the corrosion problem of magnesium alloys. Here, we report a novel hydroxyapatite coating induced by polydopamine obtained using the hydrothermal treatment. The surface morphology and composition of the coating were characterized by scanning electron microscopy, energy dispersive X-ray spectroscopy and X-ray diffraction. It was found that the dopamine-induced hydroxyapatite coating exhibits a more compact structure than the pure hydroxyapatite coating. Potentiodynamic polarization and simulated body fluid immersion tests demonstrated that the polydopamine-induced hydroxyapatite coating significantly reduced the corrosion rate due to the synergistic effect of the inner polydopamine layer and the outer hydroxyapatite coating. The cytocompatibility tests indicated that the composite coating significantly promoted the proliferation, adhesion and spread of osteoblasts. Thus, this coating may be a promising new approach for the surface modification of magnesium alloys.
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