期刊
COMMUNICATIONS IN STATISTICS-THEORY AND METHODS
卷 45, 期 11, 页码 3332-3343出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/03610926.2014.902225
关键词
ANOVA; decision-tree approach; Dunnett-test
资金
- EC-FP7 project ESNATS
- German Science Foundation DfG [HO1687/9]
Decision-tree approaches are commonly used in the analysis of toxicological assays. This paper considers the widely-used and recommended approach of first applying the ANOVA F-test and, if it is significant, using the many-to-one comparison procedure of Dunnett (1955). Data configurations are provided for which the F-test is not significant, but the Dunnett-test is significant. Because a conditional F-test before the Dunnett-test may increase the false negative rate, it is recommended that the ANOVA F-test not be used at all as a global pre-test. In addition, related non-parametric tests are investigated.
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