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Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes
Sergey Nejentsev et al.
SCIENCE (2009)
Impaired immune responses in the lungs of aged mice following influenza infection
Franklin R. Toapanta et al.
RESPIRATORY RESEARCH (2009)
Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-β
Martin J. Richer et al.
DIABETES (2008)
Viral Trigger for Type 1 Diabetes Pros and Cons
Christophe M. Filippi et al.
DIABETES (2008)
Case of fulminant type 1 diabetes associated with significant elevation of mumps titers
Atsushi Goto et al.
ENDOCRINE JOURNAL (2008)
Structural mechanism of RNA recognition by the RIG-l-like receptors
Mitsutoshi Yoneyama et al.
IMMUNITY (2008)
In vitro expansion improves in vivo regulation by CD4+CD25+ regulatory T cells
Jian-Guo Chai et al.
JOURNAL OF IMMUNOLOGY (2008)
Regulatory T cells prevent transfer of type 1 diabetes in NOD mice only when their antigen is present in vivo
Daniel R. Tonkin et al.
JOURNAL OF IMMUNOLOGY (2008)
Differential effects of the type I interferons α4, β, and ε on antiviral activity and vaccine efficacy
Stephanie L. Day et al.
JOURNAL OF IMMUNOLOGY (2008)
Time trends in the incidence of type 1 diabetes in Finnish children:: a cohort study
Valma Harjutsalo et al.
LANCET (2008)
Concordance for Islet Autoimmunity among Monozygotic Twins
Maria J. Redondo et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Interferon-α initiates type 1 diabetes in nonobese diabetic mice
Qing Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes
Asma Elshebani et al.
VIRUS RESEARCH (2007)
At-Risk and Recent-Onset Type 1 Diabetic Subjects Have Increased Apoptosis in the CD4+CD25+high T-Cell Fraction
Sanja Glisic-Milosavljevic et al.
PLOS ONE (2007)
Group B coxsackievirus diabetogenic phenotype correlates with replication efficiency
Toru Kanno et al.
JOURNAL OF VIROLOGY (2006)
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
Deborah J. Smyth et al.
NATURE GENETICS (2006)
Essential role of mda-5 in type IIFN responses to polyriboinosinic: polyribocytidylic acid and encephalomyocarditis picornavirus
Leonid Gitlin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice
JD Wetzel et al.
JOURNAL OF VIROLOGY (2006)
Inquiring into the differential action of interferons (IFNs):: an IFN-α2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-β
DA Jaitin et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Molecular analysis of an echovirus 3 strain isolated from an individual concurrently with appearance of islet cell and IA-2 autoantibodies
CH Williams et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2006)
Molecular mimicry, bystander activation, or viral persistence: Infections and autoimmune disease
RS Fujinami et al.
CLINICAL MICROBIOLOGY REVIEWS (2006)
Specific interactions of mouse organ proteins with the 5'untranslated region of coxsackievirus B3: Potential determinants of viral tissue tropism
PKM Cheung et al.
JOURNAL OF MEDICAL VIROLOGY (2005)
Cell type-specific involvement of RIG-I in antiviral response
H Kato et al.
IMMUNITY (2005)
Alternatively spliced soluble coxsackie-adenovirus receptors inhibit coxsackievirus infection
A Dörner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells
P Ylipaasto et al.
DIABETOLOGIA (2004)
IFNβ accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to β cells in nondiabetes-prone mice
A Alba et al.
JOURNAL OF IMMUNOLOGY (2004)
Enterovirus infections with β-cell tropic strains are frequent in siblings of children diagnosed with type 1 diabetes children and in association with elevated levels of GAD65 antibodies
G Frisk et al.
JOURNAL OF MEDICAL VIROLOGY (2004)
The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes
KM Gillespie et al.
LANCET (2004)
Type 1 diabetes islet associated antibodies in subjects infected by echovirus 16
E Cabrera-Rode et al.
DIABETOLOGIA (2003)
IL-1β, IFN-γ and TNF-α increase vulnerability of pancreatic beta cells to autoimmune destruction
G Wachlin et al.
JOURNAL OF AUTOIMMUNITY (2003)
Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: Inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence
S Tracy et al.
JOURNAL OF VIROLOGY (2002)
mda-5:: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
DC Kang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Heat capacity changes upon burial of polar and nonpolar groups in proteins
VV Loladze et al.
PROTEIN SCIENCE (2001)
Identification of alternative splice products encoded by the human coxsackie-adenovirus receptor gene
I Thoelen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
An IFN-γ-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-γ
DF Tough et al.
JOURNAL OF IMMUNOLOGY (2001)
Concordance for type 1 diabetes in identical twins is affected by insulin genotype
KA Metcalfe et al.
DIABETES CARE (2001)
Cytochrome c release, mitochondrial membrane depolarization, caspase-3 activation, and Bax-α cleavage during IFN-α-induced apoptosis in Daudi B lymphoma cells
N Yanase et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2000)
Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in β cells
W Chehadeh et al.
JOURNAL OF VIROLOGY (2000)
Acute onset of type I diabetes mellitus after severe echovirus 9 infection: Putative pathogenic pathways
GR Vreugdenhil et al.
CLINICAL INFECTIOUS DISEASES (2000)
Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes
MC Honeyman et al.
DIABETES (2000)
Coxsackievirus infection of the pancreas: Evaluation of receptor expression, pathogenesis, and immunopathology
I Mena et al.
VIROLOGY (2000)
Insulin for the world's poorest countries
JS Yudkin
LANCET (2000)
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