期刊
SCIENCE IMMUNOLOGY
卷 5, 期 49, 页码 -出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/sciimmunol.abd6160
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- Medical Research Council [MR/S019553/1] Funding Source: Medline
- MRC [MR/S019553/1] Funding Source: UKRI
In efforts to synthesize a clear understanding of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) protective immunity, antibody analysis has been paralleled by T cell studies across asymptomatic, mild, and severe COVID-19 (coronavirus disease 2019). Defining CD4 and CD8 effector functions in protection is important, considering that antibody responses appear short-lived and T cell memory is potentially more durable. To fully understand population-level immunity, screening for both antibody and T cell immunity using standardized testing methods would be beneficial.
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