相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity
Beatrice Cubitt et al.
ANTIVIRAL RESEARCH (2020)
Coronavirus Infections-More Than Just the Common Cold
Catharine I. Paules et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)
The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus
Calvin J. Gordon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
Jasper Fuk-Woo Chan et al.
LANCET (2020)
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen et al.
LANCET (2020)
A new coronavirus associated with human respiratory disease in China
Fan Wu et al.
NATURE (2020)
Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
Guangdi Li et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya et al.
NATURE MICROBIOLOGY (2020)
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
Yan Gao et al.
SCIENCE (2020)
Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro
Ka-Tim Choy et al.
ANTIVIRAL RESEARCH (2020)
Current knowledge about the antivirals remdesivir (GS-5734) and GS-441524 as therapeutic options for coronaviruses
E. Susan Amirian et al.
ONE HEALTH (2020)
Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir
Egor P. Tchesnokov et al.
VIRUSES-BASEL (2019)
Nucleoside analogues for the treatment of coronavirus infections
Andrea J. Pruijssers et al.
CURRENT OPINION IN VIROLOGY (2019)
Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors
Robert N. Kirchdoerfer et al.
NATURE COMMUNICATIONS (2019)
Development of a fluorescence-based method for the rapid determination of Zika virus polymerase activity and the screening of antiviral drugs
Yanira Saez-Alvarez et al.
SCIENTIFIC REPORTS (2019)
New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections
Erik De Clercq
CHEMISTRY-AN ASIAN JOURNAL (2019)
Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia
Mart Toots et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics
Sabue Mulangu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies
B. G. Murphy et al.
VETERINARY MICROBIOLOGY (2018)
RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution
Sangita Venkataraman et al.
VIRUSES-BASEL (2018)
Virus classification - where do you draw the line?
Peter Simmonds et al.
ARCHIVES OF VIROLOGY (2018)
Polymerase assays for lead discovery: An overall review of methodologies and approaches
Amir H. Nasiri et al.
ANALYTICAL BIOCHEMISTRY (2018)
In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit
Takeshi Noshi et al.
ANTIVIRAL RESEARCH (2018)
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo(2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses
Dustin Siegel et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase
Yousuke Furuta et al.
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2017)
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
Timothy P. Sheahan et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Comparative interactomics for virus-human proteinprotein interactions: DNA viruses versus RNA viruses
Saliha Durmus et al.
FEBS OPEN BIO (2017)
Approved Antiviral Drugs over the Past 50 Years
Erik De Clercq et al.
CLINICAL MICROBIOLOGY REVIEWS (2016)
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
Travis K. Warren et al.
NATURE (2016)
SARS and MERS: recent insights into emerging coronaviruses
Emmie de Wit et al.
NATURE REVIEWS MICROBIOLOGY (2016)
Fluorometric RdRp assay with self-priming RNA
Fatih Kocabas et al.
VIRUS GENES (2015)
Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
Auda A. Eltahla et al.
VIRUSES-BASEL (2015)
Identifying Initiation and Elongation Inhibitors of Dengue Virus RNA Polymerase in a High-Throughput Lead-Finding Campaign
Thomas M. Smith et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
Preclinical Characterization of BMS-791325, an Allosteric Inhibitor of Hepatitis C Virus NS5B Polymerase
Julie A. Lemm et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2
Michael P. Clark et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Discovery of a Novel Bottlenose Dolphin Coronavirus Reveals a Distinct Species of Marine Mammal Coronavirus in Gammacoronavirus
Patrick C. Y. Woo et al.
JOURNAL OF VIROLOGY (2014)
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430
Travis K. Warren et al.
NATURE (2014)
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
Lorenzo Subissi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
Jasper F. W. Chan et al.
JOURNAL OF INFECTION (2013)
A Fluorescence-Based High-Throughput Screen to Identify Small Compound Inhibitors of the Genotype 3a Hepatitis C Virus RNA Polymerase
Auda A. Eltahla et al.
JOURNAL OF BIOMOLECULAR SCREENING (2013)
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors
Grace Campagnola et al.
ANTIVIRAL RESEARCH (2011)
A Fluorescence-Based Alkaline Phosphatase-Coupled Polymerase Assay for Identification of Inhibitors of Dengue Virus RNA-Dependent RNA Polymerase
Pornwaratt Niyomrattanakit et al.
JOURNAL OF BIOMOLECULAR SCREENING (2011)
A cell-based reporter assay for inhibitor screening of hepatitis C virus RNA-dependent RNA polymerase
Jin-Ching Lee et al.
ANALYTICAL BIOCHEMISTRY (2010)
T-705 (favipiravir) activity against lethal H5N1 influenza A viruses
Maki Kiso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity
Ching-Yao Su et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 Protein
Min Qing et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Identification and characterization of coumestans as novel HCVNS5B polymerase inhibitors
Neerja Kaushik-Basu et al.
NUCLEIC ACIDS RESEARCH (2008)
A fluorescence polarization-based screening assay for nucleic acid polymerase elongation activity
Santano P. Mestas et al.
ANALYTICAL BIOCHEMISTRY (2007)
High-throughput screening of RNA polymerase inhibitors using a fluorescent UTP analog
Jyothi Bhat et al.
JOURNAL OF BIOMOLECULAR SCREENING (2006)
A second, non-canonical RNA-dependent RNA polymerase in SARS coronavirus
Isabelle Imbert et al.
EMBO JOURNAL (2006)
Mechanisms of action of ribavirin against distinct viruses
JD Graci et al.
REVIEWS IN MEDICAL VIROLOGY (2006)
Design, synthesis, and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methylcytidine, a potent inhibitor of hepatitis C virus replication
JL Clark et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Homogeneous fluorescent assay for RNA polymerase
M Kozlov et al.
ANALYTICAL BIOCHEMISTRY (2005)
Mechanism of action of T-705 against influenza virus
Y Furuta et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Molecular model of SARS coronavirus polymerase: Implications for biochemical functions and drug design
X Xu et al.
NUCLEIC ACIDS RESEARCH (2003)
Requirements for de novo initiation of RNA synthesis by recombinant flaviviral RNA-dependent RNA polymerases
CT Ranjith-Kumar et al.
JOURNAL OF VIROLOGY (2002)
The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage
AE Gorbalenya et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
RNA-dependent RNA polymerases, viruses, and RNA silencing
P Ahlquist
SCIENCE (2002)