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注意:仅列出部分参考文献,下载原文获取全部文献信息。Nucleic Acid Aptamers for Molecular Diagnostics and Therapeutics: Advances and Perspectives
Long Li et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
Bifunctional Aptamer-Doxorubicin Conjugate Crosses the Blood-Brain Barrier and Selectively Delivers Its Payload to EpCAM-Positive Tumor Cells
Joanna Macdonald et al.
NUCLEIC ACID THERAPEUTICS (2020)
Binding and Structural Properties of DNA Aptamers with VEGF-A-Mimic Activity
Toru Yoshitomi et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2020)
Axl-148b chimeric aptamers inhibit breast cancer and melanoma progression
Lorena Quirico et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)
A Chymase Inhibitory RNA Aptamer Improves Cardiac Function and Survival after Myocardial Infarction
Denan Jin et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2019)
Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells
Kazunobu Futami et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2019)
Identification and Application of an Aptamer Targeting Papillary Thyroid Carcinoma Using Tissue-SELEX
Wen Zhong et al.
ANALYTICAL CHEMISTRY (2019)
In Vitro Selection of Circular DNA Aptamers for Biosensing Applications
Meng Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)
Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment
Alanod D. AlQahtani et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Aptamers as Therapeutic Agents: Has the Initial Euphoria Subsided?
S. K. Hassel et al.
MOLECULAR DIAGNOSIS & THERAPY (2019)
Aptamer and nanomaterial based FRET biosensors: a review on recent advances (2014-2019)
Zeki Semih Pehlivan et al.
MICROCHIMICA ACTA (2019)
Plasmonic Selection of ssDNA Aptamers against Fibroblast Growth Factor Receptor
Hasan Kurt et al.
ACS COMBINATORIAL SCIENCE (2019)
Selection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells
Yacong An et al.
SCIENTIFIC REPORTS (2019)
Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells
Josue Carvalho et al.
SCIENTIFIC REPORTS (2019)
Bispecific Aptamer Induced Artificial Protein-Pairing: A Strategy for Selective Inhibition of Receptor Function
Liping Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Rapid Detection of AIB1 in Breast Cancer Cells Based on Aptamer-Functionalized Nanomotors
Mara Beltran-Gastelum et al.
CHEMPHYSCHEM (2019)
In vivo SELEX of bone targeting aptamer in prostate cancer bone metastasis model
Lingxiao Chen et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)
DNA aptamers from whole-serum SELEX as new diagnostic agents against gastric cancer
Yue Zheng et al.
RSC ADVANCES (2019)
Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model
Laia Civit et al.
SCIENTIFIC REPORTS (2019)
Putative Mechanisms Underlying High Inhibitory Activities of Bimodular DNA Aptamers to Thrombin
Elena G. Zavyalova et al.
BIOMOLECULES (2019)
Multiplex Viral Detection Platform Based on a Aptamers-Integrated Microfluidic Channel
Nileshi Saraf et al.
ACS OMEGA (2019)
Microfluidic methods for aptamer selection and characterization
Sean K. Dembowski et al.
ANALYST (2018)
Use of DNA aptamer for sandwich type detection of Listeria monocytogenes
Soo Hwan Suh et al.
ANALYTICAL BIOCHEMISTRY (2018)
Aptamer selection and application in multivalent binding-based electrical impedance detection of inactivated H1N1 virus
Chenjun Bai et al.
BIOSENSORS & BIOELECTRONICS (2018)
Nucleic acid aptamer-based methods for diagnosis of infections
Ki Soo Park
BIOSENSORS & BIOELECTRONICS (2018)
DNA Thioaptamer with Homing Specificity to Lymphoma Bone Marrow Involvement
Junhua Mai et al.
MOLECULAR PHARMACEUTICS (2018)
A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo
Suping Li et al.
NATURE BIOTECHNOLOGY (2018)
Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines
David Porciani et al.
NATURE COMMUNICATIONS (2018)
Aptamer-Mediated Delivery and Cell-Targeting Aptamers: Room for Improvement
Amy C. Yan et al.
NUCLEIC ACID THERAPEUTICS (2018)
Aptamers in the Therapeutics and Diagnostics Pipelines
Harleen Kaur et al.
THERANOSTICS (2018)
Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2(+) Breast Cancer
Xiaolin Yu et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2018)
Exploiting Stokes and anti-Stokes type emission profiles of aptamer-functionalized luminescent nanoprobes for multiplex sensing applications
Meral Yuce et al.
CHEMISTRYSELECT (2018)
Novel RNA aptamers targeting gastrointestinal cancer biomarkers CEA, CA50 and CA72-4 with superior affinity and specificity
Qing Pan et al.
PLOS ONE (2018)
A 2′FY-RNA Motif Defines an Aptamer for Ebolavirus Secreted Protein
Shambhavi Shubham et al.
SCIENTIFIC REPORTS (2018)
Aptamers as Diagnostic Tools in Cancer
Dario Ruiz Ciancio et al.
PHARMACEUTICALS (2018)
Pharmacokinetics, pharmacodynamics and safety of aptamers
Katarina D. Kovacevic et al.
ADVANCED DRUG DELIVERY REVIEWS (2018)
Multiparameter Particle Display (MPPD): A Quantitative Screening Method for the Discovery of Highly Specific Aptamers
Jinpeng Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
High-Affinity DNA Aptamer Generation Targeting von Willebrand Factor A1-Domain by Genetic Alphabet Expansion for Systematic Evolution of Ligands by Exponential Enrichment Using Two Types of Libraries Composed of Five Different Bases
Ken-ichiro Matsunaga et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)
Aptamers as targeted therapeutics: current potential and challenges
Jiehua Zhou et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
C-C motif-ligand 2 inhibition with emapticap pegol ( NOX-E36) in type 2 diabetic patients with albuminuria
Jan Menne et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2017)
Aptamer-conjugated PEGylated quantum dots targeting epidermal growth factor receptor variant III for fluorescence imaging of glioma
Jiaze Tang et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)
FDA-Approved Oligonucleotide Therapies in 2017
Cy A. Stein et al.
MOLECULAR THERAPY (2017)
Aptamer Combined with Fluorescent Silica Nanoparticles for Detection of Hepatoma Cells
Zixi Hu et al.
NANOSCALE RESEARCH LETTERS (2017)
A thermostable D-polymerase for mirror-image PCR
Andreas Pech et al.
NUCLEIC ACIDS RESEARCH (2017)
Aptamer-based point-of-care diagnostic platforms
Abhijeet Dhiman et al.
SENSORS AND ACTUATORS B-CHEMICAL (2017)
Metastatic cancer cell and tissue-specific fluorescence imaging using a new DNA aptamet developed by Cell-SELEX
Baoyin Yuan et al.
TALANTA (2017)
Eteplirsen in the treatment of Duchenne muscular dystrophy
Kenji Rowel Q. Lim et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2017)
How to make nanobiosensors: surface modification and characterisation of nanomaterials for biosensing applications
Meral Yuce et al.
RSC ADVANCES (2017)
Aptamer Combined with Fluorescent Silica Nanoparticles for Detection of Hepatoma Cells
Zixi Hu et al.
NANOSCALE RESEARCH LETTERS (2017)
Increasing Tumor-Infiltrating T Cells through Inhibition of CXCL12 with NOX-A12 Synergizes with PD-1 Blockade
Dirk Zboralski et al.
CANCER IMMUNOLOGY RESEARCH (2017)
DNA Aptamers for the Characterization of Histological Structure of Lung Adenocarcinoma
Galina S. Zamay et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2017)
ISS-N1 MAKES THE FIRST FDA-APPROVED DRUG FOR SPINAL MUSCULAR ATROPHY
Eric W. Ottesen
TRANSLATIONAL NEUROSCIENCE (2017)
Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma
Chao Liang et al.
BIOMATERIALS (2017)
Tumor cell capture patterns around aptamer-immobilized microposts in microfluidic devices
Kangfu Chen et al.
BIOMICROFLUIDICS (2017)
Selection of DNA aptamers for extra cellular domain of human epidermal growth factor receptor 2 to detect HER2 positive carcinomas
A. Sett et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2017)
Ultrasensitive electrochemical aptasensor based on sandwich architecture for selective label-free detection of colorectal cancer (CT26) cells
Ayemeh Bagheri Hashkavayi et al.
BIOSENSORS & BIOELECTRONICS (2017)
Upconversion nanoparticles based FRET aptasensor for rapid and ultrasenstive bacteria detection
Birui Jin et al.
BIOSENSORS & BIOELECTRONICS (2017)
Development of a Bifunctional Aptamer Targeting the Transferrin Receptor and Epithelial Cell Adhesion Molecule (EpCAM) for the Treatment of Brain Cancer Metastases
Joanna Macdonald et al.
ACS CHEMICAL NEUROSCIENCE (2017)
Characterization of the specific interaction between the DNA aptamer sgc8c and protein tyrosine kinase-7 receptors at the surface of T-cells by biosensing AFM
Michael Leitner et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2017)
Amplified detection of leukemia cancer cells using an aptamer-conjugated gold-coated magnetic nanoparticles on a nitrogen-doped graphene modified electrode
Seyyed Mehdi Khoshfetrat et al.
BIOELECTROCHEMISTRY (2017)
Multifunctional nanoprobe for cancer cell targeting and simultaneous fluorescence/magnetic resonance imaging
Zhenzhen Wei et al.
ANALYTICA CHIMICA ACTA (2016)
Visual detection of cancer cells by colorimetric aptasensor based on aggregation of gold nanoparticles induced by DNA hybridization
Yasaman-Sadat Borghei et al.
ANALYTICA CHIMICA ACTA (2016)
DNA-Programmed Quantum Dot Polymerization for Ultrasensitive Molecular Imaging of Cancer Cells
Zhi Li et al.
ANALYTICAL CHEMISTRY (2016)
Dual-excitation upconverting nanoparticle and quantum dot aptasensor for multiplexed food pathogen detection
Hasan Kurt et al.
BIOSENSORS & BIOELECTRONICS (2016)
3D Cell-SELEX: Development of RNA aptamers as molecular probes for PC-3 tumor cell line
Aline G. Souza et al.
EXPERIMENTAL CELL RESEARCH (2016)
Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
Nancy J. Ganson et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
An anticoagulant too good to be true for revascularisation
Freek W. A. Verheugt
LANCET (2016)
Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial
A. Michael Lincoff et al.
LANCET (2016)
Aptamer-Functionalized Fluorescent Silica Nanoparticles for Highly Sensitive Detection of Leukemia Cells
Juntao Tan et al.
NANOSCALE RESEARCH LETTERS (2016)
A synthetic molecular system capable of mirror-image genetic replication and transcription
Zimou Wang et al.
NATURE CHEMISTRY (2016)
Ten years of anti-vascular endothelial growth factor therapy
Napoleone Ferrara et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Aptamer-Functionalized Fluorescent Silica Nanoparticles for Highly Sensitive Detection of Leukemia Cells
Juntao Tan et al.
NANOSCALE RESEARCH LETTERS (2016)
From selection hits to clinical leads: progress in aptamer discovery
Keith E. Maier et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2016)
AS1411-Induced Growth Inhibition of Glioma Cells by Up-Regulation of p53 and Down-Regulation of Bcl-2 and Akt1 via Nucleolin
Ye Cheng et al.
PLOS ONE (2016)
Trends in aptamer selection methods and applications
Meral Yuce et al.
ANALYST (2015)
Specific Inhibition of MicroRNA Processing Using L-RNA Aptamers
Jonathan T. Sczepanski et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Simultaneous Imaging of Two Different Cancer Biomarkers Using Aptamer-Conjugated Quantum Dots
Jonghwan Lee et al.
SENSORS (2015)
Aptamers and Their Applications in Nanomedicine
Hongguang Sun et al.
SMALL (2015)
Selection and Characterization of DNA Aptamers Targeting All Four Serotypes of Dengue Viruses
Heng-Li Chen et al.
PLOS ONE (2015)
Multistate Point- Prevalence Survey of Health Care- Associated Infections
Shelley S. Magill et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys
Frank Schwoebel et al.
BLOOD (2013)
Use of Oligonucleotide Aptamer Ligands to Modulate the Function of Immune Receptors
Eli Gilboa et al.
CLINICAL CANCER RESEARCH (2013)
Hematopoietic Stem and Progenitor Cell Mobilization in Mice and Humans by a First-in-Class Mirror-Image Oligonucleotide Inhibitor of CXCL12
A. Vater et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
CD28 Aptamers as Powerful Immune Response Modulators
Fernando Pastor et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
Aptamers: Problems, Solutions and Prospects
A. V. Lakhin et al.
ACTA NATURAE (2013)
Inhibition of von Willebrand factor by ARC1779 in patients with acute thrombotic thrombocytopenic purpura
Petra Jilina-Stohlawetz et al.
THROMBOSIS AND HAEMOSTASIS (2011)
Effect of 3′-end capping of aptamer with various 2′,4′-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamers
Yuuya Kasahara et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
First Clinical Application of an Actively Reversible Direct Factor IXa Inhibitor as an Anticoagulation Strategy in Patients Undergoing Percutaneous Coronary Intervention
Mauricio G. Cohen et al.
CIRCULATION (2010)
In vivo selection of tumor-targeting RNA motifs
Jing Mi et al.
NATURE CHEMICAL BIOLOGY (2010)
Aptamers as therapeutics
Anthony D. Keefe et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery
Larry Gold et al.
PLOS ONE (2010)
A randomised pilot trial of the anti-von Willebrand factor aptamer ARC1779 in patients with type 2b von Willebrand disease
Bernd Jilma et al.
THROMBOSIS AND HAEMOSTASIS (2010)
The Shorter the Better: Reducing Fixed Primer Regions of Oligonucleotide Libraries for Aptamer Selection
Weihua Pan et al.
MOLECULES (2009)
The aptamer ARC1779 is a potent and specific inhibitor of von willebrand factor mediated ex vivo platelet function in acute myocardial infarction
Alexander O. Spiel et al.
PLATELETS (2009)
Micromagnetic selection of aptamers in microfluidic channels
Xinhui Lou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
First-in-human evaluation of anti-von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers
James C. Gilbert et al.
CIRCULATION (2007)
First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology - A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity
Christopher K. Dyke et al.
CIRCULATION (2006)
Selection of RNA aptamers against recombinant transforming growth factor-β type III receptor displayed on cell surface
Shoji P. Ohuchi et al.
BIOCHIMIE (2006)
Pegaptanib sodium for neovascular age-related macular degeneration - Two-year safety results of the two prospective, multicenter, controlled clinical trials
Donald J. D'Amico
OPHTHALMOLOGY (2006)
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
EWM Ng et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
RNA aptamers selected against DNA polymerase beta inhibit the polymerase activities of DNA polymerases beta and kappa
Leonid V. Gening et al.
NUCLEIC ACIDS RESEARCH (2006)
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
HS Du et al.
NATURE (2002)