期刊
CANCERS
卷 12, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/cancers12071787
关键词
cancer; mitochondria; mitochondrial transfer; tunneling nanotubes; tumor microenvironment
类别
资金
- Czech Science Foundation [GA CR 19-25354Y]
- Institutional Development Plan of University of Ostrava [IRP03_2018-2020]
- New Directions of Biomedical Research in the Ostrava Region [CZ.02.1.01/0.0/0.0/18_069/0010060, SGS03/LF/2019-2020, SGS03/PrF/2019-2020]
- ERDF-Project ENOCH [CZ.02.1.01/0.0/0.0/16_019/0000868]
Cell-to-cell communication is a fundamental process in every multicellular organism. In addition to membrane-bound and released factors, the sharing of cytosolic components represents a new, poorly explored signaling route. An extraordinary example of this communication channel is the direct transport of mitochondria between cells. In this review, we discuss how intercellular mitochondrial transfer can be used by cancer cells to sustain their high metabolic requirements and promote drug resistance and describe relevant molecular players in the context of current and future cancer therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据