相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Drug databases and their contributions to drug repurposing
Yosef Masoudi-Sobhanzadeh et al.
GENOMICS (2020)
Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models
Santiago Ruiz et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Future treatments for hereditary hemorrhagic telangiectasia
Florian Robert et al.
ORPHANET JOURNAL OF RARE DISEASES (2020)
Efficacy and Safety of a 0.1% Tacrolimus Nasal Ointment as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia: A Double-Blind, Randomized, Placebo-Controlled, Multicenter Trial
Sophie Dupuis-Girod et al.
JOURNAL OF CLINICAL MEDICINE (2020)
Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia
Marie E. Faughnan et al.
ANGIOGENESIS (2019)
SMAD4 rare variants in individuals and families with thoracic aortic aneurysms and dissections
Xue-Yan Duan et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2019)
Sclerotherapy and Topical Nasal Propranolol: An Effective and Safe Therapy for HHT-Epistaxis
Santos Esteban-Casado et al.
LARYNGOSCOPE (2019)
Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasia
Elisabetta Buscarini et al.
ORPHANET JOURNAL OF RARE DISEASES (2019)
Octreotide for gastrointestinal bleeding in hereditary hemorrhagic telangiectasia: A prospective case series
Steven Kroon et al.
AMERICAN JOURNAL OF HEMATOLOGY (2019)
Somatic Mutations in Vascular Malformations of Hereditary Hemorrhagic Telangiectasia Result in Bi-allelic Loss of ENG or ACVRL1
Daniel A. Snellings et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
Prospective pilot study of Floseal® for the treatment of anterior epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT)
John M. Lee et al.
JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY (2019)
Efficacy of TIMOLOL nasal spray as a treatment for epistaxis in hereditary hemorrhagic telangiectasia. A double-blind, randomized, placebo-controlled trial
Sophie Dupuis-Girod et al.
SCIENTIFIC REPORTS (2019)
Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension
N. Sommer et al.
PULMONARY CIRCULATION (2018)
Tacrolimus rescues the signaling and gene expression signature of endothelial ALK1 loss-of-function and improves HHT vascular pathology
Santiago Ruiz et al.
HUMAN MOLECULAR GENETICS (2017)
Topical propranolol improves epistaxis in patients with hereditary hemorrhagic telangiectasia - a preliminary report
Meir Mei-Zahav et al.
JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY (2017)
Selective effects of oral antiangiogenic tyrosine kinase inhibitors on an animal model of hereditary hemorrhagic telangiectasia
Y. H. Kim et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2017)
Prevalence and predictors of anemia in hereditary hemorrhagic telangiectasia
Raj S. Kasthuri et al.
AMERICAN JOURNAL OF HEMATOLOGY (2017)
Improvement in hereditary hemorrhagic telangiectasia after treatment with the multi-kinase inhibitor Sunitinib
Freya Droege et al.
ANNALS OF HEMATOLOGY (2016)
Topical application of timolol decreases the severity and frequency of epistaxis in patients who have previously undergone nasal dermoplasty for hereditary hemorrhagic telangiectasia
Keiichi Ichimura et al.
AURIS NASUS LARYNX (2016)
Effect of Topical Intranasal Therapy on Epistaxis Frequency in Patients With Hereditary Hemorrhagic Telangiectasia A Randomized Clinical Trial
Kevin J. Whitehead et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Effect of Bevacizumab Nasal Spray on Epistaxis Duration in Hereditary Hemorrhagic Telangectasia A Randomized Clinical Trial
Sophie Dupuis-Girod et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Can Iron Treatments Aggravate Epistaxis in Some Patients With Hereditary Hemorrhagic Telangiectasia?
Claire L. Shovlin et al.
LARYNGOSCOPE (2016)
Hereditary hemorrhagic telangiectasia: to transplant or not to transplant?
Sophie Dupuis-Girod et al.
LIVER INTERNATIONAL (2016)
Bazedoxifene, a new orphan drug for the treatment of bleeding in hereditary haemorrhagic telangiectasia
Roberto Zarrabeitia et al.
THROMBOSIS AND HAEMOSTASIS (2016)
Research on potential biomarkers in hereditary hemorrhagic telangiectasia
Luisa-Maria Botella et al.
FRONTIERS IN GENETICS (2015)
Intranasal submucosal bevacizumab for epistaxis in hereditary hemorrhagic telangiectasia: A double-blind, randomized, placebo-controlled trial
Dominik Riss et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2015)
Pulmonary Arteriovenous Malformations
Claire L. Shovlin
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Improvement in hereditary hemorrhagic telangiectasia after treatment with the phosphoinositide 3-kinase inhibitor BKM120
Urban W. Geisthoff et al.
ANNALS OF HEMATOLOGY (2014)
Tranexamic acid for epistaxis in hereditary hemorrhagic telangiectasia patients: a European cross-over controlled trial in a rare disease
S. Gaillard et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2014)
ELLIPSE Study A Phase 1 study evaluating the tolerance of bevacizumab nasal spray in the treatment of epistaxis in hereditary hemorrhagic telangiectasia
S. Dupuis-Girod et al.
MABS (2014)
Treatment of epistaxis in hereditary hemorrhagic telangiectasia with tranexamic acid - a double-blind placebo-controlled cross-over phase IIIB study
Urban W. Geisthoff et al.
THROMBOSIS RESEARCH (2014)
BMP9 Mutations Cause a Vascular-Anomaly Syndrome with Phenotypic Overlap with Hereditary Hemorrhagic Telangiectasia
Whitney L. Wooderchak-Donahue et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: Implications for the treatment and prevention of osteoporosis
Erik R. Nelson et al.
BONE (2013)
Topical timolol for the treatment of epistaxis in hereditary hemorrhagic telangiectasia
Scott E. Olitsky
AMERICAN JOURNAL OF OTOLARYNGOLOGY (2012)
Bevacizumab in Patients With Hereditary Hemorrhagic Telangiectasia and Severe Hepatic Vascular Malformations and High Cardiac Output
Sophie Dupuis-Girod et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)
Propranolol as antiangiogenic candidate for the therapy of hereditary haemorrhagic telangiectasia
Virginia Albinana et al.
THROMBOSIS AND HAEMOSTASIS (2012)
Metabolism of Ophthalmic Timolol: New Aspects of an Old Drug
Marjo Volotinen et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2011)
Effects of genistein on early-stage cutaneous wound healing
Eunkyo Park et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Immunosuppressor FK506 Increases Endoglin and Activin Receptor-Like Kinase 1 Expression and Modulates Transforming Growth Factor-β1 Signaling in Endothelial Cells
Virginia Albinana et al.
MOLECULAR PHARMACOLOGY (2011)
Anti-estrogen therapy for hereditary hemorrhagic telangiectasia - a long-term clinical trial
Eitan Yaniv et al.
RHINOLOGY (2011)
Propranolol in the treatment of infantile hemangioma: clinical effectiveness, risks, and recommendations
I. Sanchez-Carpintero et al.
ACTAS DERMO-SIFILIOGRAFICAS (2011)
Hereditary haemorrhagic telangiectasia Pathophysiology, diagnosis and treatment
Claire L. Shovlin
BLOOD REVIEWS (2010)
Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action
C. H. Storch et al.
BRITISH JOURNAL OF DERMATOLOGY (2010)
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia
Franck Lebrin et al.
NATURE MEDICINE (2010)
Estrogen therapy for hereditary haemorrhagic telangiectasia (HHT): Effects of raloxifene, on Endoglin and ALK1 expression in endothelial cells
Virginia Albinana et al.
THROMBOSIS AND HAEMOSTASIS (2010)
Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms
Mohammad Athar et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)
Silencing or Fueling Metastasis with VEGF Inhibitors: Antiangiogenesis Revisited
Sonja Loges et al.
CANCER CELL (2009)
Antiestrogen Therapy for Hereditary Hemorrhagic Telangiectasia: A Double-Blind Placebo-Controlled Clinical Trial
Eitan Yaniv et al.
LARYNGOSCOPE (2009)
Receptor activator of nuclear factor kappa B ligand and osteoprotegerin regulation of bone remodeling in health and disease
Ann E. Kearns et al.
ENDOCRINE REVIEWS (2008)
Bevacizumab reverses need for liver transplantation in hereditary hemorrhagic telangiectasia
Andrew Mitchell et al.
LIVER TRANSPLANTATION (2008)
Propranolol for severe hemangiomas of infancy
Christine Leaute-Labreze et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Elevated factor VIII in hereditary haernorrhagic telangiectasia (HHT): Association with venous thromboembolism
Claire L. Shovlin et al.
THROMBOSIS AND HAEMOSTASIS (2007)
Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT):: Regulation of ALK-I/endoglin pathway in endothelial cells
Africa Fernandez-L et al.
THROMBOSIS AND HAEMOSTASIS (2007)
A fourth locus for hereditary hemorrhagic telangiectasia maps to chromosome 7
Pinar Bayrak-Toydemir et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2006)
Biology of vascular endothelial growth factors
Himadri Roy et al.
FEBS LETTERS (2006)
Regression of cutaneous and gastrointestinal telangiectasia with sirolimus and aspirin in a patient with hereditary hemorrhagic telangiectasia
VC McAlister
ANNALS OF INTERNAL MEDICINE (2006)
Dramatic improvement in hereditary hemorrhagic telangiectasia after treatment with the vascular endothelial growth factor (VEGF) antagonist bevacizumab
Dimitri Flieger et al.
ANNALS OF HEMATOLOGY (2006)
A new locus for hereditary haemorrhagic telangiectasia (HHT3) maps to chromosome 5
SG Cole et al.
JOURNAL OF MEDICAL GENETICS (2005)
Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration - Twelve-week results of an uncontrolled open-label clinical study
S Michels et al.
OPHTHALMOLOGY (2005)
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telanglectasia associated with mutations in MADH4 (SMAD4)
CJ Gallione et al.
LANCET (2004)
Evidence of small-bowel involvement in hereditary hemorrhagic telangiectasia:: a capsule-endoscopic study
M Ingrosso et al.
ENDOSCOPY (2004)
Efficacy of tranexamic acid in a patient with hereditary hemorrhagic telangiectasia and massive epistaxis
AP del Molino et al.
MEDICINA CLINICA (2004)
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
H Hurwitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Vascular endothelial growth factor serum levels are elevated in patients with hereditary hemorrhagic telangiectasia
A Cirulli et al.
ACTA HAEMATOLOGICA (2003)
Hereditary hemorrhagic telangiectasia (Osler's disease). An interdisciplinary challenge
UW Geisthoff et al.
HNO (2002)
Efficacy of unusually high doses of tranexamic acid for the treatment of epistaxis in hereditary hemorrhagic telangiectasia.
C Sabbà et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition
MJ Cross et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2001)
分享论文
