4.8 Article

Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors

Jordan L. Doman et al.

NATURE BIOTECHNOLOGY (2020)

Article Multidisciplinary Sciences

Expanding the genome-targeting scope and the site selectivity of high-precision base editors

Junjie Tan et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants

Russell T. Walton et al.

SCIENCE (2020)

Letter Biotechnology & Applied Microbiology

CRISPResso2 provides accurate and rapid genome editing sequence analysis

Kendell Clement et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Engineering of high-precision base editors for site-specific single nucleotide replacement

Junjie Tan et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

Julian Grunewald et al.

NATURE (2019)

Article Multidisciplinary Sciences

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Changyang Zhou et al.

NATURE (2019)

Article Multidisciplinary Sciences

Search-and-replace genome editing without double-strand breaks or donor DNA

Andrew V. Anzalone et al.

NATURE (2019)

Article Multidisciplinary Sciences

Expanding C-T base editing toolkit with diversified cytidine deaminases

Tian-Lin Cheng et al.

NATURE COMMUNICATIONS (2019)

Article Biotechnology & Applied Microbiology

Performance of neural network basecalling tools for Oxford Nanopore sequencing

Ryan R. Wick et al.

GENOME BIOLOGY (2019)

Article Biotechnology & Applied Microbiology

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

Luke W. Koblan et al.

NATURE BIOTECHNOLOGY (2018)

Article Multidisciplinary Sciences

Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA

Atanu Maiti et al.

NATURE COMMUNICATIONS (2018)

Article Biotechnology & Applied Microbiology

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities

Jason M. Gehrke et al.

NATURE BIOTECHNOLOGY (2018)

Review Genetics & Heredity

Base editing: precision chemistry on the genome and transcriptome of living cells

Holly A. Rees et al.

NATURE REVIEWS GENETICS (2018)

Article Multidisciplinary Sciences

Targeting fidelity of adenine and cytosine base editors in mouse embryos

Hye Kyung Lee et al.

NATURE COMMUNICATIONS (2018)

Article Biotechnology & Applied Microbiology

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions

Y. Bill Kim et al.

NATURE BIOTECHNOLOGY (2017)

Article Multidisciplinary Sciences

Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G

Michael Morse et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

ClinVar: public archive of interpretations of clinically relevant variants

Melissa J. Landrum et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Multidisciplinary Sciences

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor et al.

NATURE (2016)

Article Multidisciplinary Sciences

The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme

Shraddha Sharma et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

APOBEC3G Inhibits HIV-1 RNA Elongation by Inactivating the Viral Trans-Activation Response Element

Roni Nowarski et al.

JOURNAL OF MOLECULAR BIOLOGY (2014)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Biochemistry & Molecular Biology

The Local Dinucleotide Preference of APOBEC3G Can Be Altered from 5′-CC to 5′-TC by a Single Amino Acid Substitution

Anurag Rathore et al.

JOURNAL OF MOLECULAR BIOLOGY (2013)

Article Biotechnology & Applied Microbiology

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

Kristian Cibulskis et al.

NATURE BIOTECHNOLOGY (2013)

Article Biochemical Research Methods

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran et al.

NATURE PROTOCOLS (2013)

Article Biochemical Research Methods

Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs

Christopher T. Saunders et al.

BIOINFORMATICS (2012)

Article Biochemistry & Molecular Biology

Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A

Michael A. Carpenter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna et al.

GENOME RESEARCH (2010)

Article Multidisciplinary Sciences

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

Lauren G. Holden et al.

NATURE (2008)

Article Multidisciplinary Sciences

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

Kuan-Ming Chen et al.

NATURE (2008)

Review Biotechnology & Applied Microbiology

The AID/APOBEC family of nucleic acid mutators

Silvestro G. Conticello

GENOME BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

Q Yu et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

DNA determination mediates innate immunity to retroviral infection

RS Harris et al.