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John L. Robinson et al.
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Yang Liu et al.
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Yu Gao et al.
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Victoria Larsson et al.
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Robert D. Moir et al.
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Harald Hampel et al.
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Javier Olazaran et al.
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Raffaele Nardone et al.
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Viviana Versace et al.
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Maciej Banach et al.
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Biomarkers in subtypes of mild cognitive impairment and subjective cognitive decline
Carl F. Eliassen et al.
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Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis
Vitaliy Ovod et al.
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Eungseok Oh et al.
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Petr Kocis et al.
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S. Abushakra et al.
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Vincenzo De Luca et al.
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Kyung Duck Lee et al.
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Homotaurine in Parkinson's disease
Lucia Ricciardi et al.
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Clinical Features of Alzheimer Disease With and Without Lewy Bodies
Eun Joo Chung et al.
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Gennaro Pagano et al.
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John F. Crary et al.
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Ada M. Tata et al.
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Honnotaurine induces measurable changes of short latency afferent inhibition in a group of mild cognitive impairment individuals
Alessandro Martorana et al.
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Lynn Rochester et al.
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Robert D. Bell et al.
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Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease
David M. Holtzman et al.
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The potential protective effect of tramiprosate (homotaurine) against Alzheimer's disease: a review
Carlo Caltagirone et al.
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The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Guy M. McKhann et al.
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The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Marilyn S. Albert et al.
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Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study)
Paul S. Aisen et al.
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Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?
Yaroslau Compta et al.
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Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: The Alzhemedtm (Tramiprosate) experience
D. Saumier et al.
JOURNAL OF NUTRITION HEALTH & AGING (2009)
Effect of tramiprosate in patients with mild-to-moderate alzheimer's disease: Exploratory analyses of the MRI sub-group of the alphase study
S. Gauthier et al.
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Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease
Joseph L. Price et al.
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Targeting soluble Aβ peptide with Tramiprosate for the treatment of brain amyloidosis
Francine Gervais et al.
NEUROBIOLOGY OF AGING (2007)
Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia
Gustavo C. Roman et al.
NEUROBIOLOGY OF AGING (2006)
A Phase II study targeting amyloid-β with 3APS in mild-to-moderate Alzheimer disease
P. S. Aisen et al.
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A phase 2 study of tramiprosate for cerebral amyloid angiopathy
Steven M. Greenberg et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2006)
Immunology and immunotherapy of Alzheimer's disease
HL Weiner et al.
NATURE REVIEWS IMMUNOLOGY (2006)
Mild cognitive impairment as a diagnostic entity
RC Petersen
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J Raber et al.
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Apolipoprotein E epsilon 4 in an autopsy series of various dementing disorders
Annette Skraep Nielsen et al.
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Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease
JC Morris et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2001)