期刊
FRONTIERS IN IMMUNOLOGY
卷 11, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2020.01558
关键词
interleukin-17; cytokine; sepsis; inflammatory response; immune response
类别
资金
- National Natural Science Foundation of China [81873946, 81974293, 81730057]
- Key Project of Military Medical Innovation Program of Chinese PLA [18CXZ026]
- National Key Research and Development Program of China [2017YFC1103302]
- Natural Science Foundation of Zhejiang Province [LY20H150011]
The interleukin (IL)-17 family includes six structure-related cytokines (A-F). To date, majority of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer. Several recent studies have indicated that IL-17A is a biomarker as well as a therapeutic target in sepsis. In the current review, we summarize the biological functions of IL-17, including IL-17-mediated responses and signal transduction pathways, with particular emphasis on clinical relevance to sepsis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据