Antihyperglycemic and Antihyperlipidemic Effects of Lippia Citriodora in Rats

Aim: The study was conducted to assess the antidiabetic and antihyperlipidemic effects of Lippia citriodora. Background: Lippia citriodora Kunth (Verbenaceae) is a medicinal plant with many traditional uses. Objective: The goal of this study was to investigate the antidiabetic activity of aqueous extract of Lippia citriodora and its capacity to improve the lipid profile in diabetic rats. Methods: Normal and diabetic rats were treated orally for 15 days by the leaves aqueous extract of Lippia citriodora (LCLAE) (100 mg/kg). The whole glucose utilization and liver architecture were also Received: February 09, 2020 Revised: April 27, 2020 evaluated. The in vitro antioxidant activity of LCLAE was also assessed. Results: LCLAE lowered blood glucose and lipid levels in all groups. Moreover, LCLAE ameliorated the liver structure and exhibited antioxidant activity. Conclusion: In conclusion, this study demonstrates the hypoglycemic and antihyperlipidemic effects of LCLAE in rats.

Automated summary

The study showed that the aqueous extract of Lippia citriodora has hypoglycemic and antihyperlipidemic effects in rats, improving liver structure and exhibiting antioxidant activity.