4.2 Article

Macromolecular crystallography beamlines at the Canadian Light Source: building on success

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出版社

INT UNION CRYSTALLOGRAPHY
DOI: 10.1107/S2059798320007603

关键词

macromolecular crystallography; beamline; double crystal; multi-layer monochromator; Canadian Light Source

资金

  1. Canada Foundation for Innovation
  2. Natural Sciences and Engineering Research Council of Canada
  3. National Research Council Canada
  4. Canadian Institutes of Health Research
  5. Government of Saskatchewan
  6. University of Saskatchewan

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The Canadian Macromolecular Crystallography Facility (CMCF) consists of two beamlines dedicated to macromolecular crystallography: CMCF-ID and CMCF-BM. After the first experiments were conducted in 2006, the facility has seen a sharp increase in usage and has produced a significant amount of data for the Canadian crystallographic community. Upgrades aimed at increasing throughput and flux to support the next generation of more demanding experiments are currently under way or have recently been completed. At CMCF-BM, this includes an enhanced monochromator, automounter software upgrades and a much faster detector. CMCF-ID will receive a major upgrade including a new undulator, a new monochromator and new optics to stably focus the beam onto a smaller sample size, as well as a brand-new detector.

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