期刊
COLORECTAL DISEASE
卷 18, 期 6, 页码 603-611出版社
WILEY
DOI: 10.1111/codi.13253
关键词
Colorectal surgery; ERAS; complication; counselling
资金
- Department of Gastrointestinal and Emergency Surgery, Haukeland University Hospital, Bergen, Norway
AimThe aim of this randomized clinical trial was to compare patients treated using a multimodal approach [enhanced recovery after surgery (ERAS)], with a special focus on counselling, to patients treated in a standard conventional care pathway, who underwent elective colorectal resection. MethodIn a single-centre trial, adult patients eligible for open or laparoscopic colorectal resection were randomized to an ERAS programme or standard care. The primary end-point was postoperative total hospital stay. Identical discharge criteria were defined for both treatment groups. Secondary end-points included postoperative complications, postoperative C-reactive protein levels, postoperative hospital stay, readmission rate and mortality. All parameters were recorded before operation, on the day of surgery and daily thereafter until discharge. ResultsTotal hospital stay was significantly shorter among patients randomized to ERAS than among the standard group [median 5days (range 2-50days) vs median 8days (range 2-48days); P=0.001]. The two treatment groups exhibited similar outcomes regarding overall major and minor morbidity, reoperation rate, readmission rate and 30-day mortality. There were also no differences in tolerance of enteral nutrition or in the inflammatory response, as reflected by postoperative C-reactive protein levels. ConclusionERAS care was associated with a significantly shorter length of hospital stay. Without any difference in surgical or general complications, tolerance of enteral nutrition or postoperative C-reactive protein levels, peri-operative information and guidance for ensuring that patients comply with the ERAS approach appear to be important factors to reduce the length of hospital stay.
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