相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Airway Surface Liquid Has Innate Antiviral Activity That Is Reduced in Cystic Fibrosis
Abigail R. Berkebile et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)
Single dose escalation studies with inhaled POL6014, a potent novel selective reversible inhibitor of human neutrophil elastase, in healthy volunteers and subjects with cystic fibrosis
P. Barth et al.
JOURNAL OF CYSTIC FIBROSIS (2020)
Targeting Proteases in Cystic Fibrosis Lung Disease Paradigms, Progress, and Potential
Michael C. McKelvey et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)
Pulmonary Outcomes Associated with Long-Term Azithromycin Therapy in Cystic Fibrosis
Dave P. Nichols et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)
Airway profile of bioactive lipids predicts early progression of lung disease in cystic fibrosis
Hamed Horati et al.
JOURNAL OF CYSTIC FIBROSIS (2020)
Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges
Krishna Rajarathnam et al.
FRONTIERS IN IMMUNOLOGY (2020)
The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis
Tim Rosenow et al.
EUROPEAN RESPIRATORY JOURNAL (2019)
Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation
Shravan Morla
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
The Laminin Interactome: A Multifactorial Laminin-Binding Strategy by Nontypeable Haemophilus influenzae for Effective Adherence and Colonization
Yu-Ching Su et al.
JOURNAL OF INFECTIOUS DISEASES (2019)
On the Process of Discovering Leads That Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients
Shravan Morla et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Muco-Obstructive Lung Diseases
Richard C. Boucher
NEW ENGLAND JOURNAL OF MEDICINE (2019)
The non-anticoagulant promise of heparin and its mimetics
Barbara Mulloy
CURRENT OPINION IN PHARMACOLOGY (2019)
IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis
Gang Chen et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
RAGE and AXL expression following secondhand smoke (SHS) exposure in mice
Kary Y. F. Tsai et al.
EXPERIMENTAL LUNG RESEARCH (2019)
Pseudomonas aeruginosa uses multiple receptors for adherence to laminin during infection of the respiratory tract and skin wounds
Magnus Paulsson et al.
SCIENTIFIC REPORTS (2019)
Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis
Robert D. Gray et al.
THORAX (2018)
Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets
Bradley H. Rosen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)
Therapeutic use of heparin and derivatives beyond anticoagulation in patients with bronchial asthma or COPD
Janis K. Shute et al.
CURRENT OPINION IN PHARMACOLOGY (2018)
The mucus bundles responsible for airway cleaning are retained in cystic fibrosis and by cholinergic stimulation
Anna Ermund et al.
EUROPEAN RESPIRATORY JOURNAL (2018)
Synthesized Heparan Sulfate Competitors Attenuate Pseudomonas aeruginosa Lung Infection
Nicola Ivan Lore et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Molecular principles for heparin oligosaccharide-based inhibition of neutrophil elastase in cystic fibrosis
Apparao B. Kummarapurugu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies
Brooke L. Farrugia et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2018)
Inflammation in cystic fibrosis: An update
Erica A. Roesch et al.
PEDIATRIC PULMONOLOGY (2018)
Neutrophil elastase correlates with increased sphingolipid content in cystic fibrosis sputum
Sophia Karandashova et al.
PEDIATRIC PULMONOLOGY (2018)
Inhaled nebulised unfractionated heparin improves lung function in moderate to very severe COPD: A pilot study
Janis K. Shute et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2018)
Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing
Danielle M. Clancy et al.
CELL REPORTS (2018)
Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway
Mohamed A. Ghonim et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2018)
A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis
Jeremiah A. Alt et al.
PLOS ONE (2018)
Prevention of sinonasal inflammation by a synthetic glycosaminoglycan
Abigail Pulsipher et al.
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2017)
Inhaled Heparin: Therapeutic Efficacy and Recent Formulations
Ayca Yildiz-Pekoz et al.
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY (2017)
New Applications of Heparin and Other Glycosaminoglycans
Marcelo Lima et al.
MOLECULES (2017)
Gel-forming mucins form distinct morphologic structures in airways
Lynda S. Ostedgaard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Sulfated hyaluronan attenuates inflammatory signaling pathways in macrophages involving induction of antioxidants
Florent Jouy et al.
PROTEOMICS (2017)
Sulfated dehydropolymer of caffeic acid: In vitro anti-lung cell death activity and in vivo intervention in emphysema induced by VEGF receptor blockade
Tien M. Truong et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2017)
LL-37 causes cell death of human nasal epithelial cells, which is inhibited with a synthetic glycosaminoglycan
Andrew J. Thomas et al.
PLOS ONE (2017)
2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity
Shuo Zheng et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2017)
Nebulized anticoagulants in lung injury in critically ill patients-an updated systematic review of preclinical and clinical studies
Jenny Juschten et al.
ANNALS OF TRANSLATIONAL MEDICINE (2017)
Innate and Adaptive Immunity in Cystic Fibrosis
Emanuela M. Bruscia et al.
CLINICS IN CHEST MEDICINE (2016)
Inhaled alpha1-proteinase inhibitor therapy in patients with cystic fibrosis
Amit Gaggar et al.
JOURNAL OF CYSTIC FIBROSIS (2016)
A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis
Justin R. Savage et al.
PLOS ONE (2016)
Acute pulmonary exacerbation and lung function decline in patients with cystic fibrosis: high-mobility group box 1 (HMGB1) between inflammation and infection
V. Chirico et al.
CLINICAL MICROBIOLOGY AND INFECTION (2015)
The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung
Matthew S. Twigg et al.
MEDIATORS OF INFLAMMATION (2015)
Origins of Cystic Fibrosis Lung Disease
David A. Stoltz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Non-Anticoagulant Fractions of Enoxaparin Suppress Inflammatory Cytokine Release from Peripheral Blood Mononuclear Cells of Allergic Asthmatic Individuals
Madhur D. Shastri et al.
PLOS ONE (2015)
NETs and CF Lung Disease: Current Status and Future Prospects
Robert D. Gray et al.
ANTIBIOTICS-BASEL (2015)
2-O, 3-O-Desulfated Heparin Inhibits Neutrophil Elastase-Induced HMGB-1 Secretion and Airway Inflammation
Kathryn L. Griffin et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Inhaled Anticoagulation Regimens for the Treatment of Smoke Inhalation-Associated Acute Lung Injury: A Systematic Review
Andrew C. Miller et al.
CRITICAL CARE MEDICINE (2014)
Partially-desulfated heparin improves survival in Pseudomonas pneumonia by enhancing bacterial clearance and ameliorating lung injury
Lokesh Sharma et al.
JOURNAL OF IMMUNOTOXICOLOGY (2014)
Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction
Ding Xu et al.
ACS CHEMICAL BIOLOGY (2013)
Increased expression of senescence markers in cystic fibrosis airways
Bernard M. Fischer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice
Jin-Ah Park et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel Function In Vitro and In Vivo
Mathieu Le Gars et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Iron accumulates in the lavage and explanted lungs of cystic fibrosis patients
Andrew J. Ghio et al.
JOURNAL OF CYSTIC FIBROSIS (2013)
Sulfation Patterns Determine Cellular Internalization of Heparin-Like Polysaccharides
Karthik Raman et al.
MOLECULAR PHARMACEUTICS (2013)
Risk Factors for Bronchiectasis in Children with Cystic Fibrosis
Peter D. Sly et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Sputum Biomarkers of Inflammation and Lung Function Decline in Children with Cystic Fibrosis
Scott D. Sagel et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice
Jakob Axelsson et al.
BLOOD (2012)
Efficacy, safety and effect on biomarkers of AZD9668 in cystic fibrosis
J. Stuart Elborn et al.
EUROPEAN RESPIRATORY JOURNAL (2012)
Sputum Biomarkers and the Prediction of Clinical Outcomes in Patients with Cystic Fibrosis
Theodore G. Liou et al.
PLOS ONE (2012)
Nebulized anticoagulants for acute lung injury - a systematic review of preclinical and clinical investigations
Pieter R. Tuinman et al.
CRITICAL CARE (2012)
Heparin changes the conformation of high-mobility group protein 1 and decreases its affinity toward receptor for advanced glycation endproducts in vitro
Yan Ling et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2011)
Pulmonary Proteases in the Cystic Fibrosis Lung Induce Interleukin 8 Expression from Bronchial Epithelial Cells via a Heme/Meprin/Epidermal Growth Factor Receptor/Toll-like Receptor Pathway
Sonya Cosgrove et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Heparan Sulfate Is Essential for High Mobility Group Protein 1 (HMGB1) Signaling by the Receptor for Advanced Glycation End Products (RAGE)
Ding Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Novel Sulfated Polysaccharides Disrupt Cathelicidins, Inhibit RAGE and Reduce Cutaneous Inflammation in a Mouse Model of Rosacea
Jianxing Zhang et al.
PLOS ONE (2011)
Inhibition of SARS Pseudovirus Cell Entry by Lactoferrin Binding to Heparan Sulfate Proteoglycans
Jianshe Lang et al.
PLOS ONE (2011)
The Involvement of Glycosaminoglycans in Airway Disease Associated with Cystic Fibrosis
Emer P. Reeves et al.
THESCIENTIFICWORLDJOURNAL (2011)
Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands
Narayanam V. Rao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
Safety and Tolerability of Inhaled Heparin in Idiopathic Pulmonary Fibrosis
Philipp Markart et al.
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY (2010)
Human Neutrophil Elastase-Mediated Cleavage Sites of MMP-9 and TIMP-1: Implications to Cystic Fibrosis Proteolytic Dysfunction
Patricia L. Jackson et al.
MOLECULAR MEDICINE (2010)
Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial
Barry Dixon et al.
CRITICAL CARE (2010)
Leukocyte Elastase Induces Lung Epithelial Apoptosis via a PAR-1-, NF-κB-, and p53-Dependent Pathway
Tomoko Suzuki et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)
Neutrophil Elastase Increases Airway Epithelial Nonheme Iron Levels
Bernard M. Fischer et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2009)
Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-Infected Cystic Fibrosis Lung Are Due to Neutrophil Elastase Degradation
Sinead Weldon et al.
JOURNAL OF IMMUNOLOGY (2009)
Proteases and cystic fibrosis
Judith A. Voynow et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Elafin, an Elastase-specific Inhibitor, Is Cleaved by Its Cognate Enzyme Neutrophil Elastase in Sputum from Individuals with Cystic Fibrosis
Nicolas Guyot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Unfractionated heparin reduces the elasticity of sputum from patients with cystic fibrosis
Victoria J. Broughton-Head et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
New insights into the inhibition of human neutrophil elastase by heparin
Jean L. Spencer et al.
BIOCHEMISTRY (2006)
Hypertonic saline enhances neutrophil elastase release through activation of P2 and A3 receptors
Y Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Inhaled heparin in cystic fibrosis
DJ Serisier et al.
EUROPEAN RESPIRATORY JOURNAL (2006)
A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis
MR Elkins et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport
RA Caldwell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting
A Naggi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
High-mobility group box 1 protein (HMGB): Nuclear weapon in the immune arsenal
MT Lotze et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
JS Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Neutrophil elastase induces mucus cell metaplasia in mouse lung
JA Voynow et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Impaired innate host defense causes susceptibility to respiratory virus infections in cystic fibrosis
S Zheng et al.
IMMUNITY (2003)
Effect of chondroitinase ABC on purulent sputum from cystic fibrosis and other patients
IA Khatri et al.
PEDIATRIC RESEARCH (2003)
Effect of inhaled heparin on lung function and coagulation in healthy volunteers
KE Bendstrup et al.
EUROPEAN RESPIRATORY JOURNAL (2002)
Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5
MC Dechecchi et al.
JOURNAL OF VIROLOGY (2001)
分享论文
