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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis
Petar Marinkovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Staged decline of neuronal function in vivo in an animal model of Alzheimer's disease
Christine Grienberger et al.
NATURE COMMUNICATIONS (2012)
The essential role of AMPA receptor GluA2 subunit RNA editing in the normal and diseased brain
Amanda Wright et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2012)
Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis
Laura Ferraiuolo et al.
BRAIN (2011)
Reduction in the Motoneuron Inhibitory/Excitatory Synaptic Ratio in an Early-Symptomatic Mouse Model of Amyotrophic Lateral Sclerosis
Carmen R. Sunico et al.
BRAIN PATHOLOGY (2011)
IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1
J. Aebischer et al.
CELL DEATH AND DIFFERENTIATION (2011)
Reduced GABAergic Inhibition Explains Cortical Hyperexcitability in the Wobbler Mouse Model of ALS
Jose Luis Nieto-Gonzalez et al.
CEREBRAL CORTEX (2011)
Motoneuron subtypes show specificity in glycine receptor channel abnormalities in a transgenic mouse model of amyotrophic lateral sclerosis
Qing Chang et al.
CHANNELS (2011)
Three Groups of Interneurons Account for Nearly 100% of Neocortical GABAergic Neurons
Bernardo Rudy et al.
DEVELOPMENTAL NEUROBIOLOGY (2011)
Evidence that Compromised K+ Spatial Buffering Contributes to the Epileptogenic Effect of Mutations in the Human Kir4.1 Gene (KCNJ10)
Nadia Nabil Haj-Yasein et al.
GLIA (2011)
Activation of Interferon Signaling Pathways in Spinal Cord Astrocytes from an ALS Mouse Model
Rengang Wang et al.
GLIA (2011)
Spinal Inhibitory Interneuron Pathology Follows Motor Neuron Degeneration Independent of Glial Mutant Superoxide Dismutase 1 Expression in SOD1-ALS Mice
Mehdi Hossaini et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
Corticospinal Motor Neurons and Related Subcerebral Projection Neurons Undergo Early and Specific Neurodegeneration in hSOD1G93A Transgenic ALS Mice
P. Hande Oezdinler et al.
JOURNAL OF NEUROSCIENCE (2011)
Glycine Receptor Channels in Spinal Motoneurons Are Abnormal in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
Qing Chang et al.
JOURNAL OF NEUROSCIENCE (2011)
Transcranial static magnetic field stimulation of the human motor cortex
Antonio Oliviero et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis
K. A. Quinlan et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Amyotrophic lateral sclerosis
Matthew C. Kiernan et al.
LANCET (2011)
Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy
George Z. Mentis et al.
NEURON (2011)
How Inhibition Shapes Cortical Activity
Jeffry S. Isaacson et al.
NEURON (2011)
Disease-Related Changes in the Cerebrospinal Fluid Metabolome in Amyotrophic Lateral Sclerosis Detected by GC/TOFMS
Anna Wuolikainen et al.
PLOS ONE (2011)
Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1G93A Mouse Model of ALS
Angelo C. Lepore et al.
PLOS ONE (2011)
Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis
Pablo Diaz-Amarilla et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo
Sophia T. Papadeas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Extracellular glutamate: functional compartments operate in different concentration ranges
Khaled Moussawi et al.
FRONTIERS IN SYSTEMS NEUROSCIENCE (2011)
Calcium dysregulation in amyotrophic lateral sclerosis
Julian Grosskreutz et al.
CELL CALCIUM (2010)
Unique Contributions of Distinct Cholinergic Projections to Motor Cortical Plasticity and Learning
J. M. Conner et al.
CEREBRAL CORTEX (2010)
Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target
Sian C. Barber et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects
Mathilde Faideau et al.
HUMAN MOLECULAR GENETICS (2010)
Upregulation of persistent sodium conductances in familial ALS
Steve Vucic et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)
Influence of Short-Interval Intracortical Inhibition on Short-Interval Intracortical Facilitation in Human Primary Motor Cortex
Yuichiro Shirota et al.
JOURNAL OF NEUROPHYSIOLOGY (2010)
The Largest Group of Superficial Neocortical GABAergic Interneurons Expresses Ionotropic Serotonin Receptors
SooHyun Lee et al.
JOURNAL OF NEUROSCIENCE (2010)
Sublayer-specific microcircuits of corticospinal and corticostriatal neurons in motor cortex
Charles T. Anderson et al.
NATURE NEUROSCIENCE (2010)
Mitochondrial dysfunction and intracellular calcium dysregulation in ALS
Hibiki Kawamata et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2010)
Reduced VGLUT2 expression increases motor neuron viability in Sod1(G93A) mice
Hanna Wootz et al.
NEUROBIOLOGY OF DISEASE (2010)
Membrane Potential Dynamics of GABAergic Neurons in the Barrel Cortex of Behaving Mice
Luc J. Gentet et al.
NEURON (2010)
Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase
John Mitchell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Noradrenergic modulation of intrinsic and synaptic properties of lumbar motoneurons in the neonatal rat spinal cord
Maylis Tartas et al.
FRONTIERS IN NEURAL CIRCUITS (2010)
Glycinergic Innervation of Motoneurons Is Deficient in Amyotrophic Lateral Sclerosis Mice A Quantitative Confocal Analysis
Qing Chang et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Increase in presynaptic territory of C-terminals on lumbar motoneurons of G93A SOD1 mice during disease progression
A. H. Pullen et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Sensory involvement in the SOD1-G93A mouse model of amyotrophic lateral sclerosis
Yan-Su Guo et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2009)
Defining the mechanisms that underlie cortical hyperexcitability in amyotrophic lateral sclerosis
Steve Vucic et al.
EXPERIMENTAL NEUROLOGY (2009)
Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis
Massimo Pieri et al.
EXPERIMENTAL NEUROLOGY (2009)
Early Excitability Changes in Lumbar Motoneurons of Transgenic SOD1G85R and SOD1G93A-Low Mice
Arnaud Pambo-Pambo et al.
JOURNAL OF NEUROPHYSIOLOGY (2009)
Effects of short interval intracortical inhibition and intracortical facilitation on short interval intracortical facilitation in human primary motor cortex
Aparna Wagle-Shukla et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice
Smita Saxena et al.
NATURE NEUROSCIENCE (2009)
Chronic elevation of extracellular glutamate due to transport blockade is innocuous for spinal motoneurons in vivo
Luis B. Tovar-y-Romo et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity
Laskaro Zagoraiou et al.
NEURON (2009)
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
Iga Wegorzewska et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Descending pathways in motor control
Roger N. Lemon
ANNUAL REVIEW OF NEUROSCIENCE (2008)
Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis
Steve Vucic et al.
BRAIN (2008)
Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
Maria C. N. Marchetto et al.
CELL STEM CELL (2008)
Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation
Francesco Paolo Di Giorgio et al.
CELL STEM CELL (2008)
GABAA receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis
Irene Carunchio et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's disease
Stefano Taverna et al.
JOURNAL OF NEUROSCIENCE (2008)
Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis
Brigitte van Zundert et al.
JOURNAL OF NEUROSCIENCE (2008)
Mitochondrial dysfunction in S0D1G93A-bearing astrocytes promotes motor neuron degeneration:: Prevention by mitochondrial-targeted antioxidants
Patricia Cassina et al.
JOURNAL OF NEUROSCIENCE (2008)
Preferential motor unit loss in the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis
J. Hegedus et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Analysis of double discharges in amyotrophic lateral sclerosis
Maria Piotrkiewicz et al.
MUSCLE & NERVE (2008)
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease
Angelo C. Lepore et al.
NATURE NEUROSCIENCE (2008)
In vivo two-photon voltage-sensitive dye imaging reveals top-down control of cortical layers 1 and 2 during wakefulness
B. Kuhn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
Marc Aurel Busche et al.
SCIENCE (2008)
Clinical, electrophysiologic, and pathologic evidence for sensory abnormalities in ALS
M. Hammad et al.
NEUROLOGY (2007)
Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic Potentiation
Biljana Djukic et al.
JOURNAL OF NEUROSCIENCE (2007)
D-Serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis
Jumpei Sasabe et al.
EMBO JOURNAL (2007)
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity
Philip Van Damme et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Extracellular glutamate concentration in hippocampal slice
Melissa A. Herman et al.
JOURNAL OF NEUROSCIENCE (2007)
Generalised sensory system abnormalities in amyotrophic lateral sclerosis: a European multicentre study
K. Pugdahl et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2007)
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
Makiko Nagai et al.
NATURE NEUROSCIENCE (2007)
Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis
Cyril Bories et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei
Marylka Uusisaari et al.
JOURNAL OF NEUROPHYSIOLOGY (2007)
Neuronal intermediate filaments and ALS: A new look at an old question
Shangxi Xiao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
L. Van den Bosch et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Increased nodal persistent Na+ currents in human neuropathy and motor neuron disease estimated by latent addition
Noriko Tamura et al.
CLINICAL NEUROPHYSIOLOGY (2006)
Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis
Melanie Kaiser et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Cellular excitability and the regulation of functional neuronal identity: From gene expression to neuromodulation
David J. Schulz et al.
JOURNAL OF NEUROSCIENCE (2006)
ALS:: A disease of motor neurons and their nonneuronal neighbors
Sverine Boillee et al.
NEURON (2006)
Functional changes in astroglial cells in epilepsy
Devin K. Binder et al.
GLIA (2006)
Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1G93A mice
Andrea C. Pardo et al.
EXPERIMENTAL NEUROLOGY (2006)
Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid:: implications for AMPA receptor-mediated excitotoxicity in ALS
Hui Sun et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Axonal excitability properties in amyotrophic lateral sclerosis
Steve Vucic et al.
CLINICAL NEUROPHYSIOLOGY (2006)
Serotonergic mechanisms in amyotrophic lateral sclerosis
Reuven Sandyk
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2006)
Distal excitability changes in motor axons in amyotrophic lateral sclerosis
Miho Nakata et al.
CLINICAL NEUROPHYSIOLOGY (2006)
Differential expression of GABAA and glycine receptors in ALS-resistant vs. ALS-vulnerable motoneurons:: possible implications for selective vulnerability of mononeurons
Louis-Etienne Lorenzo et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Glia-derived D-serine controls NMDA receptor activity and synaptic memory
Aude Panatier et al.
CELL (2006)
Altered axonal excitability properties in amyotrophic lateral sclerosis: impaired potassium channel function related to disease stage
K Kanai et al.
BRAIN (2006)
Serotonin as a modulator of glutamate- and GABA-mediated neurotransmission: Implications in physiological functions and in pathology
L Ciranna
CURRENT NEUROPHARMACOLOGY (2006)
Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF
S Pun et al.
NATURE NEUROSCIENCE (2006)
Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
JY Shin et al.
JOURNAL OF CELL BIOLOGY (2005)
Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS
MR Turner et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2005)
Cerebrospinal fluid from amyotrophic lateral sclerosis patients preferentially elevates intracellular calcium and toxicity in motor neurons via AMPA/kainate receptor
I Sen et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2005)
Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS:: studies with [11C]flumazenil PET
MR Turner et al.
BRAIN (2005)
Nerve conduction studies: Essentials and pitfalls in practice
A Mallik et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2005)
Mammalian motor neurons corelease glutamate and acetylcholine at central synapses
H Nishimaru et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Increased persistent Na+ current and its effect on excitability in motoneurones cultured from mutant SOD1 mice
JJ Kuo et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Excitability profile of motor evoked potentials and silent periods
DY Kim et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2005)
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
JD Rothstein et al.
NATURE (2005)
AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo
JC Corona et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice
JJ Kuo et al.
JOURNAL OF NEUROPHYSIOLOGY (2004)
Interneurons of the neocortical inhibitory system
H Markram et al.
NATURE REVIEWS NEUROSCIENCE (2004)
Hyperexcitable dendrites in motoneurons and their neuromodulatory control during motor behavior
CJ Heckman et al.
TRENDS IN NEUROSCIENCES (2003)
Distribution of GABAA receptor mRNA in the motor cortex of ALS patients
S Petri et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice
H Guo et al.
HUMAN MOLECULAR GENETICS (2003)
The motor infrastructure: From ion channels to neuronal networks
S Grillner
NATURE REVIEWS NEUROSCIENCE (2003)
In vivo two-photon calcium imaging of neuronal networks
C Stosiek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Low concentrations of glutamate induce apoptosis in cultured neurons:: Implications for amyrotrophic lateral sclerosis
C Cid et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2003)
Changes in motor cortex inhibition over time in patients with amyotrophic lateral sclerosis
G Zanette et al.
JOURNAL OF NEUROLOGY (2002)
Degeneration of corticospinal and bulbospinal systems in the superoxide dismutase 1G93A G1H transgenic mouse model of familial amyotrophic lateral sclerosis
DW Zang et al.
NEUROSCIENCE LETTERS (2002)
Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis
PR Heath et al.
MUSCLE & NERVE (2002)
Motor unit hyperexcitability in amyotrophic lateral sclerosis vs amino acids acting as neurotransmitters
A Kostera-Pruszczyk et al.
ACTA NEUROLOGICA SCANDINAVICA (2002)
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
DS Howland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1
JS Deitch et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2002)
Two phases of intracortical inhibition revealed by transcranial magnetic threshold tracking
RJ Fisher et al.
EXPERIMENTAL BRAIN RESEARCH (2002)
Neuromodulatory transmitter systems in the cortex and their role in cortical plasticity
Q Gu
NEUROSCIENCE (2002)
Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels
C Bendotti et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Lactate reduces glutamate-induced neurotoxicity in rat cortex
J Ros et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2001)
The motor cortex and amyotrophic lateral sclerosis
A Eisen et al.
MUSCLE & NERVE (2001)
Paired transcranial magnetic stimulation protocols reveal a pattern of inhibition and facilitation in the human parietal cortex
M Oliveri et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor
JP Mothet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutase
GM Alexander et al.
JOURNAL OF NEUROCHEMISTRY (2000)