期刊
COLLOIDS AND SURFACES B-BIOINTERFACES
卷 145, 期 -, 页码 643-652出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfb.2016.05.008
关键词
Chitosan; Epigallocatechin gallate; Rectorite; Layer-by-layer; Cellulose nanofibrous mats; Antimicrobial activity
资金
- National High Technology Research and Development Program of China (863 program) [2015AA020313]
- National Natural Science Foundation of China [51473125]
- China Postdoctoral Science Foundation [2015M582237]
- Natural Science Foundation of Hubei Province of China [2015CFA017]
Cellulose electrospun nanofibrous mats coated with bilayers of chitosan (CS) and epigallocatechin gal late (EGCG) or with bilayers of CS-rectorite (REC) composite (CS-REC) and EGCG were fabricated via layer-by-layer (LBL) self-assembly technique. LBL-structured cellulose nanofibers still maintained three dimension fiber structure according to the observation from scanning electron microscopy images. The average diameter of nanofibers were enlarged with the addition of REC. X-ray photoelectron spectroscopy results confirmed the deposition of CS and CS-REC onto the corresponding mats. The tensile strength and rate of elongation at break of LBL-structured nanofibers had no difference from those of uncoated nanofibers. The encapsulation efficiency and loading capacity of nanofibers were enhanced in the presence of REC. In addition the in-vitro cumulative release profiles of EGCG indicate that the addition of REC delayed the release of EGCG. Antimicrobial assay demonstrated the inhibitory effects of CS and EGCG on the growth of Staphylococcus aureus. Meanwhile the CS-REC composites improved the antimicrobial effects of CS and EGCG by adsorption of bacteria to the surface of REC then enhancement of exposure of bacteria to EGCG and the matrix of CS. (C) 2016 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据