期刊
TOXINS
卷 12, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/toxins12060408
关键词
Staphylococcus aureus; toxins; vaccines; monoclonal antibodies
资金
- NIH/NIAID [R01 AI139172]
Staphylococcus aureusasymptomatically colonizes approximately 30-50% of the population and is a leading cause of bacteremia, bone/joint infections, and skin infections in the US.S. aureushas become a major public health threat due to antibiotic resistance and an increasing number of failed vaccine attempts. To develop new anti-staphylococcal preventive therapies, it will take a more thorough understanding of the current roleS. aureusvirulence factors play in contributing to human disease. This review focuses on the clinical association of individual toxins withS. aureusinfection as well as attempted treatment options. Further understanding of these associations will increase understanding of toxins and their importance toS. aureuspathogenesis.
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