期刊
COLLOID JOURNAL
卷 78, 期 5, 页码 586-595出版社
PLEIADES PUBLISHING INC
DOI: 10.1134/S1061933X16050045
关键词
-
资金
- Russian Foundation for Basic Research [16-03-00118]
It has been shown that mesoporous nanocontainers from SiO2 may be obtained by the sol-gel synthesis using drug (Miramistin) micelles as a template. The nanocontainers resulting from the combination of the stages of their synthesis and loading are characterized by a very high content of the drug (no less than 0.9 g per 1 g of SiO2). The kinetics of Miramistin desorption from the mesoporous particles into an aqueous medium has been studied under static and quasi-dynamic conditions. The desorption has been shown to rather strongly depend on pH. Possible mechanisms of the desorption process have been discussed.
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