期刊
CLINICS IN GERIATRIC MEDICINE
卷 32, 期 1, 页码 113-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cger.2015.08.001
关键词
Prostate cancer; Elderly; Geriatric; Localized; Metastatic; Oncology; Surgery; Radiation
The impact of localized prostate cancer in the elderly depends on disease aggressiveness and life expectancy. In men with localized prostate cancer, those with low-risk disease or a shorter life expectancy should be managed expectantly, whereas those with long life expectancy or more aggressive disease may benefit from curative treatment. Comorbidity and quality-of-life concerns are key considerations during the selection of therapeutic modalities in the elderly in localized and metastatic settings. A variety of new agents have changed the therapeutic landscape in castrate-resistant prostate cancer, but their benefits need to be considered alongside their side effects and cost.
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