Recent advances in the synthesis of Quinazoline analogues as Anti-TB agents

Quinazoline analogues are one of the important nitrogen containing heterocycles that have significant bioactivity as well as found in a plethora of natural products. Tuberculosis is one of the serious universal health threats caused by Mycobacterium tuberculosis (MTB) and primarily affects the lungs. Due to their significant bioactivity and natural occurrences of quinazolines, researchers are trying to synthesize new quinazoline analogues which may have significant potency against tuberculosis. This particular review summarizes recent development of different types of quinazoline bearing analogues as anti-tubercular (anti-TB) agents and their synthesis with structure-activity relationship.