期刊
TETRAHEDRON LETTERS
卷 61, 期 31, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2020.152200
关键词
Gold catalysis; O-alkynylbenzaldehyde; [4+2]-cycloaddition; Benzopyrilium; 3,4-dihydrobenzo[f]isoqu nolin-1(2H)-one
资金
- National Natural Science Foundation of China [21502093]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
An efficient synthetic method to prepare 3,4-dihydrobenzo[f]isoquinolin-1(2H)-ones through gold(I)-catalyzed intramolecular [4 + 2] benzannulation of o-(N-tethered 1,6-diynyl)benzaldehydes at a low catalyst loading of 2 mol% is described. The product of 3,4-dihydrobenzo[f]isoquinolin-1(2H)-ones can be easily transformed to benzo[f]isoquinolin-1-ols by simply treating with phenylmagnesium bromide under mild conditions. The structures of compounds 2o and 2w were also ascertained by X-ray crystallographic analysis. (C) 2020 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据