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Hisham Qosa et al.
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Shilpa Narayan et al.
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Dan-Dong Li et al.
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Stacy Steinberg et al.
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A. Schubert et al.
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Lindsay Poppe et al.
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Radosveta Koldamova et al.
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Human Transporter Database: Comprehensive Knowledge and Discovery Tools in the Human Transporter Genes
Adam Y. Ye et al.
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Michael R. Jablonski et al.
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Alteration in P-glycoprotein at the bloodbrain barrier in the early period of MCAO in rats
Juan Cen et al.
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Jared B. Vasquez et al.
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Loqman A. Mohamed et al.
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Cerebral expression of drug transporters in epilepsy
Eleonora Aronica et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
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Danielle M. E. van Assema et al.
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Yu Zeng et al.
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Michael R. Jablonski et al.
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Michaela Meyer et al.
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Marwan N. Sabbagh et al.
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Gijs Kooij et al.
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Fredrik Lauritzen et al.
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Matthijs L. Becker et al.
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Shi Du Yan et al.
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Leon M. Tai et al.
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Bjoern Bauer et al.
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Qingguang Jiang et al.
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Alberto Lazarowski et al.
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P. Dazert et al.
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A Spudich et al.
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SE Wahrle et al.
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EA van Vliet et al.
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W Löscher et al.
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W Löscher et al.
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Blood-brain barrier dysfunction in Parkinsonian midbrain in vivo
R Kortekaas et al.
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JD Rothstein et al.
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F Zhang et al.
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MA Summers et al.
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PR Heath et al.
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FC Lam et al.
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