相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis
Tomas Castro-Dopico et al.
IMMUNITY (2019)
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
Christopher S. Smillie et al.
CELL (2019)
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
Jerome C. Martin et al.
CELL (2019)
Intestinal epithelial cells: at the interface of the microbiota and mucosal immunity
Amelia T. Soderholm et al.
IMMUNOLOGY (2019)
Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life
Takashi Senda et al.
MUCOSAL IMMUNOLOGY (2019)
Unique invariant natural killer T cells promote intestinal polyps by suppressing TH1 immunity and promoting regulatory T cells
Y. Wang et al.
MUCOSAL IMMUNOLOGY (2018)
A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling
Christoph Schneider et al.
CELL (2018)
Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease
Holm H. Uhlig et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 36 (2018)
Advances in understanding the role of cytokines in inflammatory bowel disease
Gerolamo Bevivino et al.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY (2018)
Anti-infliximab Antibodies with Neutralizing Capacity in Patients with Inflammatory Bowel Disease: Distinct Clinical Implications Revealed by a Novel Assay
Roni Weisshof et al.
INFLAMMATORY BOWEL DISEASES (2016)
The microbiota in adaptive immune homeostasis and disease
Kenya Honda et al.
NATURE (2016)
MEKK2 mediates an alternative β-catenin pathway that promotes bone formation
Matthew Blake Greenblatt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis
Roni Nowarski et al.
CELL (2015)
Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability
Jacob S. Lee et al.
IMMUNITY (2015)
Interleukin-22 Induces Interleukin-18 Expression from Epithelial Cells during Intestinal Infection
Melba Munoz et al.
IMMUNITY (2015)
Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis
Yu Sun et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2015)
Regulatory immune cells in regulation of intestinal inflammatory response to microbiota
M. Sun et al.
MUCOSAL IMMUNOLOGY (2015)
Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages
Mingyue Wen et al.
NATURE COMMUNICATIONS (2015)
Experimental Models of Inflammatory Bowel Diseases
Patricia Kiesler et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2015)
MEKK2 regulates focal adhesion stability and motility in invasive breast cancer cells
Ahmed A. Mirza et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
IL-17A Produced by γδ T Cells Promotes Tumor Growth in Hepatocellular Carcinoma
Shoubao Ma et al.
CANCER RESEARCH (2014)
A comparative encyclopedia of DNA elements in the mouse genome
Feng Yue et al.
NATURE (2014)
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
Pawel K. Mazur et al.
NATURE (2014)
Modulation of immune development and function by intestinal microbiota
Agnieszka M. Kabat et al.
TRENDS IN IMMUNOLOGY (2014)
Cytokines in inflammatory bowel disease
Markus F. Neurath
NATURE REVIEWS IMMUNOLOGY (2014)
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
Lance W. Peterson et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Stimulatory Toll-like receptor 2 suppresses restraint stress-induced immune suppression
Dan Hu et al.
CELLULAR IMMUNOLOGY (2013)
The Interleukin-1 Family: Back to the Future
Cecilia Garlanda et al.
IMMUNITY (2013)
Interleukin-18, more than a Th1 cytokine
Daniela Novick et al.
SEMINARS IN IMMUNOLOGY (2013)
Toll-like receptor regulation of effector T lymphocyte function
Joseph M. Reynolds et al.
TRENDS IN IMMUNOLOGY (2013)
Overexpression of MEKK2 is associated with colorectal carcinogenesis
Li Jiang et al.
ONCOLOGY LETTERS (2013)
IL-17 cytokines in immunity and inflammation
Wei Jin et al.
EMERGING MICROBES & INFECTIONS (2013)
Role of TH17 cytokines in the control of colorectal cancer
Veronica De Simone et al.
ONCOIMMUNOLOGY (2013)
Mitogen-activated protein kinases in innate immunity
J. Simon C. Arthur et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Role of the gut microbiota in immunity and inflammatory disease
Nobuhiko Kamada et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
Histone Deacetylase (HDAC) 1 Controls the Expression of Beta Defensin 1 in Human Lung Epithelial Cells
Kimberley Kallsen et al.
PLOS ONE (2012)
Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation
Joseph M. Reynolds et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Kinases MEKK2 and MEKK3 Regulate Transforming Growth Factor-β-Mediated Helper T Cell Differentiation
Xing Chang et al.
IMMUNITY (2011)
Intestinal homeostasis and its breakdown in inflammatory bowel disease
Kevin J. Maloy et al.
NATURE (2011)
Genetics and pathogenesis of inflammatory bowel disease
Bernard Khor et al.
NATURE (2011)
Antigen-Independent IFN-γ Production by Human Naive CD4+ T Cells Activated by IL-12 Plus IL-18
Rachel B. Munk et al.
PLOS ONE (2011)
Inflammatory Bowel Disease
Arthur Kaser et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 28 (2010)
Mucosal T cells in gut homeostasis and inflammation
Femke van Wijk et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2010)
Interleukin-18 in Intestinal Inflammation: Friend and Foe?
Britta Siegmund
IMMUNITY (2010)
The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
Md. Hasan Zaki et al.
IMMUNITY (2010)
TL1A Produced by Lamina Propria Macrophages Induces Th1 and Th17 Immune Responses in Cooperation with IL-23 in Patients with Crohn's Disease
Nobuhiko Kamada et al.
INFLAMMATORY BOWEL DISEASES (2010)
TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice
Jose M. Gonzalez-Navajas et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1α, and TNF-α Recapitulates Some Features of Psoriasis
Karline Guilloteau et al.
JOURNAL OF IMMUNOLOGY (2010)
Regulatory Lymphocytes and Intestinal Inflammation
Ana Izcue et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Interferon-γ and the Interferon-Inducible Chemokine CXCL10 Protect Against Aneurysm Formation and Rupture
Victoria L. King et al.
CIRCULATION (2009)
ROR gamma-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F
Moritz Leppkes et al.
GASTROENTEROLOGY (2009)
A protective function for interleukin 17A in T cell-mediated intestinal inflammation
William O'Connor et al.
NATURE IMMUNOLOGY (2009)
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
T. Kobayashi et al.
GUT (2008)
The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease
Masayuki Fukata et al.
JOURNAL OF IMMUNOLOGY (2008)
T cell expression of MyD88 is required for resistance to Toxoplasma gondii
David F. LaRosa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Role of cytokines in inflammatory bowel disease
Fausto Sanchez-Munoz et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
TH 17 cells in development:: an updated view of their molecular identity and genetic programming
Chen Dong
NATURE REVIEWS IMMUNOLOGY (2008)
A global double-fluorescent cre reporter mouse
Mandar Deepak Muzumdar et al.
GENESIS (2007)
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
Daniel Mucida et al.
SCIENCE (2007)
Cutting edge: TLR2 directly triggers Th1 effector functions
Takayuki Imanishi et al.
JOURNAL OF IMMUNOLOGY (2007)
Critical role of IL-17 receptor signaling in acute TNBS-induced colitis
Z Zhang et al.
INFLAMMATORY BOWEL DISEASES (2006)
Opinion - Diversification of T-helper-cell lineages: finding the family root of IL-17-producing cells
C Dong
NATURE REVIEWS IMMUNOLOGY (2006)
Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells
A Banerjee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways
DY Zhang et al.
EMBO JOURNAL (2006)
Th17: An effector CD4 T cell lineage with regulatory T cell ties
Casey T. Weaver et al.
IMMUNITY (2006)
MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts
K Kesavan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2004)
TLR2 is expressed on activated T cells as a costimulatory receptor
M Komai-Koma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Infliximab maintenance therapy for fistulizing Crohn's disease
BE Sands et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway
K Nakamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction
ZJ Guo et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage
PV Sivakumar et al.
GUT (2002)
Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-α production in mice
T Ten Hove et al.
GASTROENTEROLOGY (2001)
MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression
B Su et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mammalian MAP kinase signalling cascades
LF Chang et al.
NATURE (2001)
Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation
JK Cheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Cell fate decision: T-helper 1 and 2 subsets in immune responses
C Dong et al.
ARTHRITIS RESEARCH (2000)