期刊
RHEUMATOLOGY INTERNATIONAL
卷 41, 期 5, 页码 987-991出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00296-020-04625-1
关键词
Sneddon Syndrome; Cerebrovascular disease; Livedo racemosa; Case report; Literature review
类别
资金
- HCA Healthcare
Sneddon Syndrome is a rare chronic condition affecting blood vessels with skin and cerebrovascular symptoms, but not exclusive to these. The diagnosis of this syndrome can be difficult and requires comprehensive assessment based on medical history, symptoms, and laboratory tests.
Herein, we report a case-based review of the Sneddon Syndrome (SS), a rare chronic condition which affects small to medium blood vessels. It is known by its skin presentation, livedo racemosa (LRC), and the relapsing cerebrovascular events. However, neither LRC nor cerebrovascular events are exclusive to SS. A 36-year-old female with history of mitral valve prolapse, hypothyroidism, Raynaud phenomenon, hypertension, migraines, and four episodes of transient ischemic attacks (TIA), presented to our clinic with new skin findings, suggestive of LRC. Based on her previous history, current presentation and skin biopsy results, she was diagnosed with SS secondary to antiphospholipid syndrome. The present report illustrates the difficulty in recognizing SS and how the heterogeneity of the disease may be contributing to the difficulty making a distinct diagnosis.
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