期刊
PROGRESS IN LIPID RESEARCH
卷 79, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.plipres.2020.101048
关键词
Neo steroids; tert-butyl; Natural; Synthetic; Neuroprotective agents; Anticancer
资金
- Russian Science Foundation [18-73-10030, 20-64-47019]
- Russian Science Foundation [20-64-47019, 18-73-10030] Funding Source: Russian Science Foundation
In this review, steroids with a tertiary butyl group, which are usually called neo steroids, are a small group of natural lipids isolated from higher plants, fungi, marine sponges, and yeast. In addition, steroids with a tertiary butyl group have been synthesized in some laboratories in Canada, USA, Europe, and Japan and their biological activity was studied. Some natural neo steroids demonstrate antitumor or hepatoprotective activities. In addition, synthetic neo steroids exhibit anticancer and neuroprotective properties. However, to confirm the above data, both practical and clinical experimental studies are necessary. Nevertheless, the results may be useful for pharmacologists, chemists, biochemists, and the pharmaceutical industry.
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