相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension
Cheng-Jun Hu et al.
EUROPEAN RESPIRATORY JOURNAL (2019)
RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia
Lindsay M. Herbert et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2018)
Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2 alpha Inhibitor
Zhiyu Dai et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)
Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension
Oleg Pak et al.
EUROPEAN RESPIRATORY JOURNAL (2018)
Rho kinase and Na+/H+ exchanger mediate endothelin-1-induced pulmonary arterial smooth musclecell proliferation and migration
John C. Huetsch et al.
PHYSIOLOGICAL REPORTS (2018)
Integrating perfusable vascular networks with a three-dimensional tissue in a microfluidic device
Yuji Nashimoto et al.
INTEGRATIVE BIOLOGY (2017)
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension
Hui Luo et al.
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2017)
A microfluidic chamber-based approach to map the shear moduli of vascular cells and other soft materials
Bela Suki et al.
SCIENTIFIC REPORTS (2017)
Aquaporin 1-mediated changes in pulmonary arterial smooth muscle cell migration and proliferation involve β-catenin
Xin Yun et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2017)
Serotonin Signaling Through the 5-HT1B Receptor and NADPH Oxidase 1 in Pulmonary Arterial Hypertension
Katie Y. Hood et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)
RhoA/Rho-Kinase in the Cardiovascular System
Hiroaki Shimokawa et al.
CIRCULATION RESEARCH (2016)
Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Mediated Redox Signaling and Vascular Remodeling by 16α-Hydroxyestrone in Human Pulmonary Artery Cells Implications in Pulmonary Arterial Hypertension
Katie Y. Hood et al.
HYPERTENSION (2016)
The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice
Pinelopi P. Kapitsinou et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
HIF2α-arginase axis is essential for the development of pulmonary hypertension
Andrew S. Cowburn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Proline-rich tyrosine kinase 2 downregulates peroxisome proliferator-activated receptor gamma to promote hypoxia-induced pulmonary artery smooth muscle cell proliferation
Kaiser M. Bijli et al.
PULMONARY CIRCULATION (2016)
NADPH oxidase 4 is not involved in hypoxia-induced pulmonary hypertension
C. Veith et al.
PULMONARY CIRCULATION (2016)
Role of Rho kinase and Na+/H+ exchange in hypoxia-induced pulmonary arterial smooth muscle cell proliferation and migration
Jasmine Walker et al.
PHYSIOLOGICAL REPORTS (2016)
Chronic hypoxia does not cause wall thickening of intra-acinar pulmonary supernumerary arteries
Kaori Oshima et al.
PHYSIOLOGICAL REPORTS (2016)
Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells
Stephen Wedgwood et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes
Steven C. Pugliese et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs
Jian Wang et al.
CARDIOVASCULAR RESEARCH (2015)
Redox Homeostasis and Mitochondrial Dynamics
Peter H. G. M. Willems et al.
CELL METABOLISM (2015)
TRANSIENT RECEPTOR POTENTIAL CHANNELS IN THE VASCULATURE
Scott Earley et al.
PHYSIOLOGICAL REVIEWS (2015)
Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension
Abdul Q. Sheikh et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension
John H. Newman et al.
NATURE COMMUNICATIONS (2015)
Regulation of Hypoxia-induced Pulmonary Hypertension by Vascular Smooth Muscle Hypoxia-Inducible Factor-1α
Molly K. Ball et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
The Aquaporin 1 C-Terminal Tail Is Required for Migration and Growth of Pulmonary Arterial Myocytes
Ning Lai et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
NADPH Oxidase 4 Is Expressed in Pulmonary Artery Adventitia and Contributes to Hypertensive Vascular Remodeling
Scott A. Barman et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)
Lysyl Oxidases Play a Causal Role in Vascular Remodeling in Clinical and Experimental Pulmonary Arterial Hypertension
Alexander H. Nave et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)
Mammalian Target of Rapamycin Complex 2 ( mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension
Dmitry A. Goncharov et al.
CIRCULATION (2014)
Adventitial Fibroblasts Induce a Distinct Proinflammatory/Profibrotic Macrophage Phenotype in Pulmonary Hypertension
Karim C. El Kasmi et al.
JOURNAL OF IMMUNOLOGY (2014)
NOX4 Mediates BMP4-Induced Upregulation of TRPC1 and 6 Protein Expressions in Distal Pulmonary Arterial Smooth Muscle Cells
Qian Jiang et al.
PLOS ONE (2014)
Recapitulation of Developing Artery Muscularization in Pulmonary Hypertension
Abdul Q. Sheikh et al.
CELL REPORTS (2014)
Vascular stiffening in pulmonary hypertension: cause or consequence? (2013 Grover Conference series)
Wei Tan et al.
PULMONARY CIRCULATION (2014)
Activation of hypoxia-inducible factor-1 in pulmonary arterial smooth muscle cells by endothelin-1
Sarah Pisarcik et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2
Jun Wan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Classical Transient Receptor Potential Channel 1 in Hypoxia-induced Pulmonary Hypertension
Monika Malczyk et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Increased p22phox/Nox4 Expression Is Involved in Remodeling Through Hydrogen Peroxide Signaling in Experimental Persistent Pulmonary Hypertension of the Newborn
Stephen Wedgwood et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Function of NADPH Oxidase 1 in Pulmonary Arterial Smooth Muscle Cells After Monocrotaline-Induced Pulmonary Vascular Remodeling
Florian Veit et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Crucial Role of ROCK2 in Vascular Smooth Muscle Cells for Hypoxia-Induced Pulmonary Hypertension in Mice
Toru Shimizu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
Effects of collagen deposition on passive and active mechanical properties of large pulmonary arteries in hypoxic pulmonary hypertension
Zhijie Wang et al.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2013)
Pro-fibrotic processes in human lung fibroblasts are driven by an autocrine/paracrine endothelinergic system
A. S. Ahmedat et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Hypoxia-Inducible Factor-1α in Pulmonary Artery Smooth Muscle Cells Lowers Vascular Tone by Decreasing Myosin Light Chain Phosphorylation
Yu-Mee Kim et al.
CIRCULATION RESEARCH (2013)
Hypoxia downregulates PPARγ via an ERK1/2-NF-κB-Nox4-dependent mechanism in human pulmonary artery smooth muscle cells
Xianghuai Lu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
New mechanisms of pulmonary arterial hypertension: role of Ca2+ signaling
Frank K. Kuhr et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Kinase-dependent activation of voltage-gated Ca2+ channels by ET-1 in pulmonary arterial myocytes during chronic hypoxia
Trevor Luke et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
Hypoxia-induced migration in pulmonary arterial smooth muscle cells requires calcium-dependent upregulation of aquaporin 1
Kyle Leggett et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
The Nox4 Inhibitor GKT137831 Attenuates Hypoxia-Induced Pulmonary Vascular Cell Proliferation
David E. Green et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Role of collagen content and cross-linking in large pulmonary arterial stiffening after chronic hypoxia
Zhijie Wang et al.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY (2012)
Hypoxia-Inducible Factors in Physiology and Medicine
Gregg L. Semenza
CELL (2012)
Role of RhoB in the Regulation of Pulmonary Endothelial and Smooth Muscle Cell Responses to Hypoxia
Beata Wojciak-Stothard et al.
CIRCULATION RESEARCH (2012)
Dynamin-Related Protein 1-Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension
Glenn Marsboom et al.
CIRCULATION RESEARCH (2012)
Endothelin-1 induces hypoxia inducible factor 1α expression in pulmonary artery smooth muscle cells
Manxiang Li et al.
FEBS LETTERS (2012)
Hypoxia induces Kv channel current inhibition by increased NADPH oxidase-derived reactive oxygen species
Manish Mittal et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
55th Bowditch Lecture: Effects of chronic hypoxia on the pulmonary circulation: Role of HIF-1
Larissa A. Shimoda
JOURNAL OF APPLIED PHYSIOLOGY (2012)
HYPOXIC PULMONARY VASOCONSTRICTION
J. T. Sylvester et al.
PHYSIOLOGICAL REVIEWS (2012)
ADAPTIVE AND MALADAPTIVE CARDIORESPIRATORY RESPONSES TO CONTINUOUS AND INTERMITTENT HYPOXIA MEDIATED BY HYPOXIA-INDUCIBLE FACTORS 1 AND 2
Nanduri R. Prabhakar et al.
PHYSIOLOGICAL REVIEWS (2012)
Endothelin-1 Augments Na+/H+ Exchange Activity in Murine Pulmonary Arterial Smooth Muscle Cells via Rho Kinase
Clark Undem et al.
PLOS ONE (2012)
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
Edsel M. Abud et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Animal models of pulmonary hypertension: Rho kinase inhibition
Amy L. Firth et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2012)
Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Regulates Thrombospondin-1 and Nox4 Expression in Hypoxia-Induced Human Pulmonary Artery Smooth Muscle Cell Proliferation
David E. Green et al.
Pulmonary Circulation (2012)
NFATc3 is required for chronic hypoxia-induced pulmonary hypertension in adult and neonatal mice
R. Bierer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)
HIF and the Lung Role of Hypoxia-inducible Factors in Pulmonary Development and Disease
Larissa A. Shimoda et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Silencing of Sodium-Hydrogen Exchanger 1 Attenuates the Proliferation, Hypertrophy, and Migration of Pulmonary Artery Smooth Muscle Cells via E2F1
Lunyin Yu et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia
Vera P. Krymskaya et al.
FASEB JOURNAL (2011)
Bone Morphogenetic Protein Receptor II Is a Novel Mediator of Endothelial Nitric-oxide Synthase Activation
Archana Gangopahyay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension
Min Li et al.
JOURNAL OF IMMUNOLOGY (2011)
The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension
Dongmin Shao et al.
PHARMACOLOGICAL RESEARCH (2011)
Hypoxia Inducible-Factor1α Regulates the Metabolic Shift of Pulmonary Hypertensive Endothelial Cells
Iwona Fijalkowska et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Hypoxia-induced proliferation of human pulmonary microvascular endothelial cells depends on epidermal growth factor receptor tyrosine kinase activation
Inimary T. Toby et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2010)
PPARγ regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-κB
Xianghuai Lu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2010)
Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension
Lynda Anderson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)
Rosiglitazone Attenuates Chronic Hypoxia-Induced Pulmonary Hypertension in a Mouse Model
Rachel E. Nisbet et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2010)
The Hypoxia-Inducible Factor-2α Is Stabilized by Oxidative Stress Involving NOX4
Isabel Diebold et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinase
David F. Meoli et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2010)
BMP signaling in vascular development and disease
Jonathan W. Lowery et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2010)
Cellular mechanisms of IL-17-induced blood-brain barrier disruption
Jula Huppert et al.
FASEB JOURNAL (2010)
The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1
Isabel Diebold et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Reconstituting Organ-Level Lung Functions on a Chip
Dongeun Huh et al.
SCIENCE (2010)
Bone Morphogenetic Protein (BMP)-4 and BMP-7 regulate differentially Transforming Growth Factor (TGF)-β1 in normal human lung fibroblasts (NHLF)
Sophie Pegorier et al.
RESPIRATORY RESEARCH (2010)
Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure
Kurt R. Stenmark et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Endothelial deletion of hypoxia-inducible factor-2α (HIF-2α) alters vascular function and tumor angiogenesis
Nicolas Skuli et al.
BLOOD (2009)
Recent advances in BMP receptor signaling
Christina Sieber et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
The science of endothelin-1 and endothelin receptor antagonists in the management of pulmonary arterial hypertension: current understanding and future studies
N. J. Davie et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2009)
Resveratrol Prevents Monocrotaline-Induced Pulmonary Hypertension in Rats
Anna Csiszar et al.
HYPERTENSION (2009)
AQP1 Is Not Only a Water Channel: It Contributes to Cell Migration through Lin7/Beta-Catenin
Elena Monzani et al.
PLOS ONE (2009)
Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes
E. Miles Whitman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia
Nikki L. Jernigan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Deficiency of the NHE1 gene prevents hypoxia-induced pulmonary hypertension and vascular remodeling
Lunyin Yu et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts
K. M. Mair et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications
E. D. Burg et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Stiffening of the Extrapulmonary Arteries From Rats in Chronic Hypoxic Pulmonary Hypertension
E. S. Drexler et al.
JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (2008)
BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes
Xudong Yang et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2007)
Chronic hypoxia-induced pulmonary hypertension does/does not lead to loss of pulmonary vasculature - Reply
John T. Berg
JOURNAL OF APPLIED PHYSIOLOGY (2007)
Ca2+ signaling in hypoxic pulmonary vasoconstriction:: effects of myosin light chain and Rho kinase antagonists
Jian Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature
Manish Mittal et al.
CIRCULATION RESEARCH (2007)
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
Sebastien Bonnet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Reactive oxygen species activate the HIF-1α promoter via a functional NFκB site
Steve Bonello et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Mechanisms of vascular smooth muscle cell migration
William T. Gerthoffer
CIRCULATION RESEARCH (2007)
Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice
Kohtaro Abe et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2006)
HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes
Larissa A. Shimoda et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
Hypoxia-induced pulmonary vascular remodeling - Cellular and molecular mechanisms
Kurt R. Stenmark et al.
CIRCULATION RESEARCH (2006)
Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells
Jian Wang et al.
CIRCULATION RESEARCH (2006)
An abnormal mitochondrial-hypoxia inducible factor-1α-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats -: Similarities to human pulmonary arterial hypertension
Sébastien Bonnet et al.
CIRCULATION (2006)
Evidence for a control of plasma serotonin levels by 5-hydroxytryptamine2B receptors in mice
J Callebert et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats
L Weigand et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91(phox))
JQ Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
Chronic hypoxia elevates intracellular pH and activates Na+/H+ exchange in pulmonary arterial smooth muscle
EJ Rios et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
Impact of HIF-1α and HIF-2α on proliferation and migration of human pulmonary artery fibroblasts in hypoxia
B Eul et al.
FASEB JOURNAL (2005)
Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension
DB Frank et al.
CIRCULATION RESEARCH (2005)
Inhibition of rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation
JM Hyvelin et al.
CIRCULATION RESEARCH (2005)
Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery
J Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)
Dysfunctional smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension
XD Yang et al.
CIRCULATION RESEARCH (2005)
Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes
DM Rodman et al.
CIRCULATION RESEARCH (2005)
Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption
S Saadoun et al.
NATURE (2005)
Acute hypoxia simultaneously induces the expression of gp91phox and endothelial nitric oxide synthase in the porcine pulmonary artery
S Muzaffar et al.
THORAX (2005)
Comparative physiology of hypoxic pulmonary hypertension: historical clues from brisket disease
J Rhodes
JOURNAL OF APPLIED PHYSIOLOGY (2005)
Inhaled rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension
T Nagaoka et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Calcium and TRP channels in pulmonary vascular smooth muscle cell proliferation
JW Landsberg et al.
NEWS IN PHYSIOLOGICAL SCIENCES (2004)
Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase
KA Fagan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin
YL Liu et al.
CIRCULATION RESEARCH (2004)
Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells -: A novel mechanism of hypoxic pulmonary hypertension
MJ Lin et al.
CIRCULATION RESEARCH (2004)
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats
T Nagaoka et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension
S Bonnet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction chronically hypoxic rats
ZI Pozeg et al.
CIRCULATION (2003)
Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation
K Howell et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Characterization of high-altitude pulmonary hypertension in the Kyrgyz: Association with angiotensin-converting enzyme genotype
AA Aldashev et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
Acute and chronic hypoxic pulmonary vasoconstriction: a central role for endothelin-1?
LA Shimoda et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2002)
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells -: role of hypoxia-inducible transcription factors
F Rose et al.
FASEB JOURNAL (2002)
Loss of HIF-2 and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
V Compernolle et al.
NATURE MEDICINE (2002)
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats - Role of increased expression and activity of voltage-gated potassium channels
ED Michelakis et al.
CIRCULATION (2002)
Altered growth responses of muscle cells from patients pulmonary artery smooth with primary pulmonary hypertension to transforming growth factor-β1 and bone morphogenetic proteins
NW Morrell et al.
CIRCULATION (2001)
Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia
LA Shimoda et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)
Ion exchange activity in pulmonary artery smooth muscle cells: the response to hypoxia
JA Madden et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)
Upregulated TRP and enhanced capacitative Ca2+ entry in human pulmonary artery myocytes during proliferation
VA Golovina et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
Direct binding of the Na-H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H+ translocation
SP Denker et al.
MOLECULAR CELL (2000)
L-type Ca2+ channels, resting [Ca2+]i, and ET-1-induced responses in chronically hypoxic pulmonary myocytes
LA Shimoda et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2000)
Contractile responses to human urotensin-II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat
MR MacLean et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Pulmonary vascular response of the coati to chronic hypoxia
WL Hanson et al.
JOURNAL OF APPLIED PHYSIOLOGY (2000)
分享论文
