4.6 Article

Estimating the size of COVID-19 epidemic outbreak

期刊

PHYSICA SCRIPTA
卷 95, 期 8, 页码 -

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IOP PUBLISHING LTD
DOI: 10.1088/1402-4896/ab9bdf

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COVID-19; Epidemiology; Mathematical modeling

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In this work, we analyze the epidemic data of cumulative infected cases collected from many countries as reported by the World Health Organization (WHO). Our inspection is motivated by the renormalization group (RG) framework. Here we propose the RG-inspired logistic function of the form alpha(E) (t) = a(1 + e(-c(t-t0)))(-n) as an epidemic strength function with n being asymmetry in the modified logistic function. We perform the non-linear least-squares analysis with data from various countries. The uncertainty for model parameters is computed using the squared root of the corresponding diagonal components of the covariance matrix. We carefully divide countries under consideration into 2 categories based on the estimation of the inflection point: the maturing phase and the growth-dominated phase. We observe that long-term estimations of cumulative infected cases of countries in the maturing phase for both n = 1 and n not equal 1 are close to each other. We find from the value of root mean squared error (RMSE) that the RG-inspired logistic model with n not equal 1 is slightly preferable in this category. We also argue that n determines the characteristic of the epidemic at an early stage. However, in the second category, the estimated asymptotic number of cumulative infected cases contain rather large uncertainty. Therefore, in the growth-dominated phase, we focus on using n = 1 for countries in this phase. Some of them are in an early stage of an epidemic with an insufficient amount of data leading to a large uncertainty on parameter fits. In terms of the accuracy of the size estimation, the results do strongly depend on limitations on data collection and the epidemic phase for each country.

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